Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Method to Extend Research in Time (MERIT) Award (R37)
Project #
5R37HL036957-15
Application #
6389013
Study Section
Special Emphasis Panel (NSS)
Program Officer
Spooner, Peter
Project Start
1986-07-01
Project End
2005-04-30
Budget Start
2001-05-01
Budget End
2002-04-30
Support Year
15
Fiscal Year
2001
Total Cost
$267,831
Indirect Cost
Name
Johns Hopkins University
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
045911138
City
Baltimore
State
MD
Country
United States
Zip Code
21218
Ardehali, Hossein; O'Rourke, Brian; Marban, Eduardo (2005) Cardioprotective role of the mitochondrial ATP-binding cassette protein 1. Circ Res 97:740-2
Ardehali, Hossein; Xue, Tian; Dong, Peihong et al. (2005) Targeting of the mitochondrial membrane proteins to the cell surface for functional studies. Biochem Biophys Res Commun 338:1143-51
Ardehali, Hossein; Chen, Zhenhui; Ko, Young et al. (2004) Multiprotein complex containing succinate dehydrogenase confers mitochondrial ATP-sensitive K+ channel activity. Proc Natl Acad Sci U S A 101:11880-5
Hsu, Kate; Seharaseyon, Jegatheesan; Dong, Peihong et al. (2004) Mutual functional destruction of HIV-1 Vpu and host TASK-1 channel. Mol Cell 14:259-67
Murata, Mitsushige; Cingolani, Eugenio; McDonald, Amy D et al. (2004) Creation of a genetic calcium channel blocker by targeted gem gene transfer in the heart. Circ Res 95:398-405
Teshima, Yasushi; Akao, Masaharu; Li, Ronald A et al. (2003) Mitochondrial ATP-sensitive potassium channel activation protects cerebellar granule neurons from apoptosis induced by oxidative stress. Stroke 34:1796-802
Teshima, Yasushi; Akao, Masaharu; Jones, Steven P et al. (2003) Uncoupling protein-2 overexpression inhibits mitochondrial death pathway in cardiomyocytes. Circ Res 93:192-200
Akao, Masaharu; O'Rourke, Brian; Teshima, Yasushi et al. (2003) Mechanistically distinct steps in the mitochondrial death pathway triggered by oxidative stress in cardiac myocytes. Circ Res 92:186-94
Akao, Masaharu; O'Rourke, Brian; Kusuoka, Hideo et al. (2003) Differential actions of cardioprotective agents on the mitochondrial death pathway. Circ Res 92:195-202
Teshima, Yasushi; Akao, Masaharu; Jones, Steven P et al. (2003) Cariporide (HOE642), a selective Na+-H+ exchange inhibitor, inhibits the mitochondrial death pathway. Circulation 108:2275-81

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