Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Method to Extend Research in Time (MERIT) Award (R37)
Project #
4R37HL048093-15
Application #
7391885
Study Section
Special Emphasis Panel (NSS)
Program Officer
Przywara, Dennis
Project Start
1993-07-01
Project End
2013-06-30
Budget Start
2008-07-15
Budget End
2009-06-30
Support Year
15
Fiscal Year
2008
Total Cost
$357,107
Indirect Cost
Name
University of Pennsylvania
Department
Anatomy/Cell Biology
Type
Schools of Medicine
DUNS #
042250712
City
Philadelphia
State
PA
Country
United States
Zip Code
19104
Lavorato, Manuela; Huang, Tai-Qin; Iyer, Venkat Ramesh et al. (2015) Dyad content is reduced in cardiac myocytes of mice with impaired calmodulin regulation of RyR2. J Muscle Res Cell Motil 36:205-14
Franzini-Armstrong, Clara (2014) Memories of Annemarie Weber. Anat Rec (Hoboken) 297:1543-7
Park, Chang Sik; Chen, Shan; Lee, Hoyong et al. (2013) Targeted ablation of the histidine-rich Ca(2+)-binding protein (HRC) gene is associated with abnormal SR Ca(2+)-cycling and severe pathology under pressure-overload stress. Basic Res Cardiol 108:344
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Schredelseker, Johann; Dayal, Anamika; Schwerte, Thorsten et al. (2009) Proper restoration of excitation-contraction coupling in the dihydropyridine receptor beta1-null zebrafish relaxed is an exclusive function of the beta1a subunit. J Biol Chem 284:1242-51
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Chopra, Nagesh; Kannankeril, Prince J; Yang, Tao et al. (2007) Modest reductions of cardiac calsequestrin increase sarcoplasmic reticulum Ca2+ leak independent of luminal Ca2+ and trigger ventricular arrhythmias in mice. Circ Res 101:617-26

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