Agency
National Institute of Health (NIH)
Institute
National Institute of Mental Health (NIMH)
Type
Method to Extend Research in Time (MERIT) Award (R37)
Project #
5R37MH035664-17
Application #
2244433
Study Section
Special Emphasis Panel (NSS)
Project Start
1980-08-01
Project End
1999-07-31
Budget Start
1996-08-01
Budget End
1997-07-31
Support Year
17
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Wadsworth Center
Department
Type
DUNS #
110521739
City
Menands
State
NY
Country
United States
Zip Code
12204
Battaglioli, Gino; Liu, Hongcheng; Hauer, Charles R et al. (2005) Glutamate decarboxylase: loss of N-terminal segment does not affect homodimerization and determination of the oxidation state of cysteine residues. Neurochem Res 30:989-1001
Martin, Sandra B; Waniewski, Robert A; Battaglioli, Gino et al. (2003) Post-mortem degradation of brain glutamate decarboxylase. Neurochem Int 42:549-54
Martin, D L; Liu, H; Martin, S B et al. (2000) Structural features and regulatory properties of the brain glutamate decarboxylases. Neurochem Int 37:111-9
Chen, C H; Colon, W; Myer, Y P et al. (2000) ATP's impact on the conformation and holoenzyme formation in relation to the regulation of brain glutamate decarboxylase. Arch Biochem Biophys 380:285-93
Battaglioli, G; Rosen, D R; Gospe Jr, S M et al. (2000) Glutamate decarboxylase is not genetically linked to pyridoxine-dependent seizures. Neurology 55:309-11
Sheikh, S N; Martin, S B; Martin, D L (1999) Regional distribution and relative amounts of glutamate decarboxylase isoforms in rat and mouse brain. Neurochem Int 35:73-80
Soghomonian, J J; Martin, D L (1998) Two isoforms of glutamate decarboxylase: why? Trends Pharmacol Sci 19:500-5
Qu, K; Martin, D L; Lawrence, C E (1998) Motifs and structural fold of the cofactor binding site of human glutamate decarboxylase. Protein Sci 7:1092-105
Martin, D L; Barke, K E (1998) Are GAD65 and GAD67 associated with specific pools of GABA in brain? Perspect Dev Neurobiol 5:119-29
Sheikh, S N; Martin, D L (1998) Elevation of brain GABA levels with vigabatrin (gamma-vinylGABA) differentially affects GAD65 and GAD67 expression in various regions of rat brain. J Neurosci Res 52:736-41

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