The focus of this project is to explore the relationship between inflammatory cells and cognitive dysfunction in populations with HIV-1 infection. Extensive work has found that a biomarker is detected in lumbar cerebrospinal fluid of HIV(+) subjects with impaired cognition. Presently there are no suitable clinical tests to identify early neuro-inflammatory injury to neurons in such disorders as HIV-1 dementia. The ability to identify and treat HIV(+) populations before the onset of irreversible brain damage is highly desirable and forms the basis for this STTR proposal. ? ? ?

Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
Small Business Technology Transfer (STTR) Grants - Phase II (R42)
Project #
3R42NS046997-02S1
Application #
6961654
Study Section
Special Emphasis Panel (ZRG1)
Program Officer
Nunn, Michael
Project Start
2004-02-15
Project End
2005-07-31
Budget Start
2004-09-15
Budget End
2005-07-31
Support Year
2
Fiscal Year
2005
Total Cost
$448,845
Indirect Cost
Name
Inflame Therapeutics, Inc.
Department
Type
DUNS #
170628619
City
Houston
State
TX
Country
United States
Zip Code
77054