The focus of this project is to explore the relationship between inflammatory cells and cognitive dysfunction in populations with HIV-1 infection. Extensive work has found that a biomarker is detected in lumbar cerebrospinal fluid of HIV(+) subjects with impaired cognition. Presently there are no suitable clinical tests to identify early neuro-inflammatory injury to neurons in such disorders as HIV-1 dementia. The ability to identify and treat HIV(+) populations before the onset of irreversible brain damage is highly desirable and forms the basis for this STTR proposal. ? ? ?

Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
Small Business Technology Transfer (STTR) Grants - Phase II (R42)
Project #
5R42NS046997-03
Application #
6972938
Study Section
Special Emphasis Panel (ZRG1-NAED (02))
Program Officer
Nunn, Michael
Project Start
2004-02-15
Project End
2007-07-31
Budget Start
2005-08-01
Budget End
2006-07-31
Support Year
3
Fiscal Year
2005
Total Cost
$1,005,479
Indirect Cost
Name
Inflame Therapeutics, Inc.
Department
Type
DUNS #
170628619
City
Houston
State
TX
Country
United States
Zip Code
77054