Abstract

This proposal is to implement the techniques of sensitivity analysis as a means to 1) quantatitvely assess the relationship between the potential and the observables calculated using molecular mechanics and dynamics; and 2)to quantitatively assess the relationship between the function of a biomolecule and its structure. These techniques will be used in the quantitative evaluation of the of reliability modelling.Phase I showed the significance of these concepts and Phase II will develop their capabilities for biomolecular modeling.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Small Business Innovation Research Grants (SBIR) - Phase II (R44)
Project #
2R44GM042267-02A1
Application #
3507946
Study Section
Special Emphasis Panel (SSS (B))
Project Start
1989-03-01
Project End
1994-02-28
Budget Start
1992-03-01
Budget End
1993-02-28
Support Year
2
Fiscal Year
1992
Total Cost
Indirect Cost

  Institution

Name
Biosym Technologies, Inc.
Department
Type
DUNS #
City
San Diego
State
CA
Country
United States
Zip Code
92121