Agency
National Institute of Health (NIH)
Institute
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Type
Institutional National Research Service Award (T32)
Project #
5T32AA007467-05
Application #
2043913
Study Section
Biochemistry, Physiology and Medicine Subcommittee (ALCB)
Project Start
1987-09-30
Project End
1993-06-30
Budget Start
1991-07-01
Budget End
1993-06-30
Support Year
5
Fiscal Year
1991
Total Cost
Indirect Cost
Name
Johns Hopkins University
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
045911138
City
Baltimore
State
MD
Country
United States
Zip Code
21218
Sanchez-Alvarez, Rosa; Martinez-Outschoorn, Ubaldo E; Lin, Zhao et al. (2013) Ethanol exposure induces the cancer-associated fibroblast phenotype and lethal tumor metabolism: implications for breast cancer prevention. Cell Cycle 12:289-301
Dippold, Rachael P; Vadigepalli, Rajanikanth; Gonye, Gregory E et al. (2013) Chronic ethanol feeding alters miRNA expression dynamics during liver regeneration. Alcohol Clin Exp Res 37 Suppl 1:E59-69
Sanchez-Alvarez, Rosa; Martinez-Outschoorn, Ubaldo E; Lamb, Rebecca et al. (2013) Mitochondrial dysfunction in breast cancer cells prevents tumor growth: understanding chemoprevention with metformin. Cell Cycle 12:172-82
Dippold, Rachael P; Vadigepalli, Rajanikanth; Gonye, Gregory E et al. (2012) Chronic ethanol feeding enhances miR-21 induction during liver regeneration while inhibiting proliferation in rats. Am J Physiol Gastrointest Liver Physiol 303:G733-43
Ding, Ming; Potter, James J; Liu, Xiaopu et al. (2010) Selenium supplementation decreases hepatic fibrosis in mice after chronic carbon tetrachloride administration. Biol Trace Elem Res 133:83-97
Aram, Ghazaleh; Potter, James J; Liu, Xiaopu et al. (2009) Deficiency of nicotinamide adenine dinucleotide phosphate, reduced form oxidase enhances hepatocellular injury but attenuates fibrosis after chronic carbon tetrachloride administration. Hepatology 49:911-9
Sysa, Polina; Potter, James J; Liu, Xiaopu et al. (2009) Transforming growth factor-beta1 up-regulation of human alpha(1)(I) collagen is mediated by Sp1 and Smad2 transacting factors. DNA Cell Biol 28:425-34
Aram, Ghazaleh; Potter, James J; Liu, Xiaopu et al. (2008) Lack of inducible nitric oxide synthase leads to increased hepatic apoptosis and decreased fibrosis in mice after chronic carbon tetrachloride administration. Hepatology 47:2051-8
Wang, Lan; Tankersley, Lynda Rennie; Tang, Mei et al. (2004) Regulation of alpha 2(I) collagen expression in stellate cells by retinoic acid and retinoid X receptors through interactions with their cofactors. Arch Biochem Biophys 428:92-8
Tang, Mei; Potter, James J; Mezey, Esteban (2003) Activation of the human alpha1(I) collagen promoter by leptin is not mediated by transforming growth factor beta responsive elements. Biochem Biophys Res Commun 312:629-33

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