This training program aims to produce a new generation of scientists, engineers and medical practitioners who are trained to possess the knowledge and skills to integrate innovations in nanotechnology and physical sciences to cancer diagnosis and treatment. Due to the complexity of cancer disease, there has been limited progress made in the field during the past few decades. It has become clear that the involvement of nano science and technology in oncology may fundamentally change our ways to diagnose and treat this lethal disease. We realized, however, that there is a serious lack of researchers who are competent of pursuing these highly interdisciplinary activities, and that the progress made in nanomedicine during the past decade depends mostly on researchers'tremendous effort in expanding their knowledge to the related areas beyond their expertise when the needs arise. We believe that by preparing our students and postdoctoral fellows for knowledge and skills in this emerging field in the early stages of their career development, we would be able to significantly expedite such endeavor in the next few years. To this extent, we have carefully assembled an interdisciplinary preceptor team consisting of 40 faculty members of different backgrounds and whose research interests are in the interdisciplinary areas between oncology, engineering, and physical sciences in six departments at University of Washington (UW) and Fred Hutchinson Cancer Research Center (FHCRC). This unique blend expertise, combined with a carefully designed curriculum, will expose trainees to an excellent combination of fundamental as well as clinically-oriented cancer research. The major components of our training activities include: 1) laboratory or clinical research in which each trainee will be co-advised by at least two faculty members, one from medical background and one from science or engineering;2) participation in a required and an elective graduate course;3) attendance in seminar programs and a clinical tumor board;4) presentations in annual symposium by students on their research progress;5) a set of enrichment activities including a journal club, and training on ethic conduct and leadership skills;6) frequent feedback from faculty to trainees and annual progress evaluation from an executive committee. We request support for 2 predoctoral students, 5 postdoctoral and 2 MD fellows every year in the duration of the program with each trainee receiving a two-year support. The participating institutions and faculty of this program have strong records in recruitment of underrepresented minorities. The training program will work with existing programs at the both institutes and make additional program specific efforts to recruit minority trainees.

Public Health Relevance

National Institute of Health (NIH)
National Cancer Institute (NCI)
Institutional National Research Service Award (T32)
Project #
Application #
Study Section
Subcommittee G - Education (NCI)
Program Officer
Lim, Susan E
Project Start
Project End
Budget Start
Budget End
Support Year
Fiscal Year
Total Cost
Indirect Cost
University of Washington
Engineering (All Types)
Schools of Engineering
United States
Zip Code
Seki, Takakazu; So, Christopher R; Page, Tamon R et al. (2018) Electrochemical Control of Peptide Self-Organization on Atomically Flat Solid Surfaces: A Case Study with Graphite. Langmuir 34:1819-1826
Erickson, Ariane E; Lan Levengood, Sheeny K; Sun, Jialu et al. (2018) Fabrication and Characterization of Chitosan-Hyaluronic Acid Scaffolds with Varying Stiffness for Glioblastoma Cell Culture. Adv Healthc Mater 7:e1800295
Mu, Qingxin; Wang, Hui; Zhang, Miqin (2017) Nanoparticles for imaging and treatment of metastatic breast cancer. Expert Opin Drug Deliv 14:123-136
Levengood, Sheeny Lan; Erickson, Ariane E; Chang, Fei-Chien et al. (2017) Chitosan-Poly(caprolactone) Nanofibers for Skin Repair. J Mater Chem B 5:1822-1833
Chiarelli, Peter A; Revia, Richard A; Stephen, Zachary R et al. (2017) Nanoparticle Biokinetics in Mice and Nonhuman Primates. ACS Nano 11:9514-9524
Phan-Lai, Vy; Dang, Yushe; Gad, Ekram et al. (2016) The Antitumor Efficacy of IL2/IL21-Cultured Polyfunctional Neu-Specific T Cells Is TNF?/IL17 Dependent. Clin Cancer Res 22:2207-16
Chang, Fei-Chien; Tsao, Ching-Ting; Lin, Anqi et al. (2016) PEG-chitosan hydrogel with tunable stiffness for study of drug response of breast cancer cells. Polymers (Basel) 8:
Zrazhevskiy, Pavel; Akilesh, Shreeram; Tai, Wanyi et al. (2016) Cross-Platform DNA Encoding for Single-Cell Imaging of Gene Expression. Angew Chem Int Ed Engl 55:8975-8
Jana, Soumen; Levengood, Sheeny K Lan; Zhang, Miqin (2016) Anisotropic Materials for Skeletal-Muscle-Tissue Engineering. Adv Mater 28:10588-10612
Hayamizu, Yuhei; So, Christopher R; Dag, Sefa et al. (2016) Bioelectronic interfaces by spontaneously organized peptides on 2D atomic single layer materials. Sci Rep 6:33778

Showing the most recent 10 out of 99 publications