This is the third competitive renewal for T32DA013911 (?HIV and Other Infectious Consequences of Substance Abuse?) and seeks funding for Years 2017-2022. The program will now be led by dual PIs: Dr. Timothy P. Flanigan (the PI for the past 15 years), who will direct mentoring and training, and Dr. Josiah D. Rich, who will direct research project development. This training grant focuses on applied clinical and substance use research in Rhode Island and beyond. Rhode Island has among the highest rates of substance use in the nation and ranks 6th in the country for overdose rates. Our substance use training program emerged from the Brown University-affiliated Miriam Hospital Immunology Center, the largest HIV care center in Southern New England, where approximately 60% of the patients engage in substance use (alcohol, cocaine, opiate, methamphetamines, and poly-substance abuse). Our program's strengths are our interdisciplinary collaborations to reduce the infectious disease consequences of substance use, including HIV, hepatitis B and C, sexually transmitted infections, and TB. This training program brings together core expertise from the Division of Infectious Diseases, the Providence-Boston Center for AIDS Research (CFAR), the Centers for Behavioral and Preventive Medicine, the Brown University Center for Statistical Studies, and the Brown University School of Public Health. This interdisciplinary training program focuses on HIV prevention and treatment, including innovative PrEP programs, and correctional health, with a primary focus on reducing the infectious consequences of substance use as well as overdose. Our mentors have strong track records in applied clinical, substance use, translational science, correctional health research, and community-engaged scholarship.

Public Health Relevance

This program trains post-doctoral fellows in clinical research to more effectively understand and manage the challenges of HIV and other infectious consequences of substance abuse. Incorporating expertise from multiple disciplines greatly enhances diagnosis, prevention and treatment research of HIV and other infectious diseases among active substance abusers and within communities that are heavily impacted by substance abuse. Community engagement is emphasized to ensure that marginalized communities benefit from advances in biomedical science.

Agency
National Institute of Health (NIH)
Institute
National Institute on Drug Abuse (NIDA)
Type
Institutional National Research Service Award (T32)
Project #
5T32DA013911-19
Application #
9931171
Study Section
Special Emphasis Panel (ZAA1)
Program Officer
Lao, Guifang
Project Start
2001-07-01
Project End
2022-06-30
Budget Start
2020-07-01
Budget End
2021-06-30
Support Year
19
Fiscal Year
2020
Total Cost
Indirect Cost
Name
Miriam Hospital
Department
Type
DUNS #
063902704
City
Providence
State
RI
Country
United States
Zip Code
02906
Ortblad, Katrina F; Musoke, Daniel K; Ngabirano, Thomson et al. (2018) Female Sex Workers Often Incorrectly Interpret HIV Self-Test Results in Uganda. J Acquir Immune Defic Syndr 79:e42-e45
Sakyi, Kwame S; Lartey, Margaret Y; Dension, Julie A et al. (2018) Low Birthweight, Retention in HIV Care, and Adherence to ART Among Postpartum Women Living with HIV in Ghana. AIDS Behav :
Aibana, Omowunmi; Franke, Molly F; Huang, Chuan-Chin et al. (2018) Vitamin E Status Is Inversely Associated with Risk of Incident Tuberculosis Disease among Household Contacts. J Nutr 148:56-62
Oldenburg, Catherine E; Chanda, Michael M; Ortblad, Katrina F et al. (2018) Effect of HIV self-testing on the number of sexual partners among female sex workers in Zambia. AIDS 32:645-652
Ortblad, Katrina F; Chanda, Michael M; Musoke, Daniel Kibuuka et al. (2018) Acceptability of HIV self-testing to support pre-exposure prophylaxis among female sex workers in Uganda and Zambia: results from two randomized controlled trials. BMC Infect Dis 18:503
Oldenburg, Catherine E; Seage, George R; Tanser, Frank et al. (2018) Antiretroviral Therapy and Mortality in Rural South Africa: A Comparison of Causal Modeling Approaches. Am J Epidemiol :
Dompreh, Albert; Tang, Xiaoli; Zhou, Jianlin et al. (2018) Effect of Genetic Variation of NAT2 on Isoniazid and SLCO1B1 and CES2 on Rifampin Pharmacokinetics in Ghanaian Children with Tuberculosis. Antimicrob Agents Chemother 62:
Ortblad, Katrina F; Kibuuka Musoke, Daniel; Ngabirano, Thomson et al. (2018) HIV self-test performance among female sex workers in Kampala, Uganda: a cross-sectional study. BMJ Open 8:e022652
Myers, Bronwyn; Bouton, Tara C; Ragan, Elizabeth J et al. (2018) Impact of alcohol consumption on tuberculosis treatment outcomes: a prospective longitudinal cohort study protocol. BMC Infect Dis 18:488
Nunn, Amy; Parker, Sharon; McCoy, Katryna et al. (2018) African American Clergy Perspectives About the HIV Care Continuum: Results From a Qualitative Study in Jackson, Mississippi. Ethn Dis 28:85-92

Showing the most recent 10 out of 235 publications