Urologic disease causes significant morbidity and lost quality of life to millions in the U.S., and these problems will only grow more burdensome to the healthcare system in our aging population. At the same time, advances in biology and medicine offer new opportunities to understand mechanisms of urologic disease and develop novel therapies for patients - promise that can only be realized through research. The goal of this training program is to cultivate and maintain the ranks of future leaders in urological research. Building upon a history of successfully training leaders in urology, the proposed training program offers opportunities to promising, young basic and clinician scientists to engage in urologic research by supporting predoctoral and postdoctoral fellows in a structured training program. Fellows will be selected from among highly qualified predoctoral candidates identified within Northwestern Ph.D. programs and solicited postdoctoral candidates, always working to attract and support candidates that fulfill Northwestern's goal of enhancing diversity. Fellows wil select from a distinguished, interdisciplinary panel of successful preceptors and enter into a rigorous training program that complements advanced scientific training with careful instruction in research integrity and fostering individual development. Two predoctoral and two postdoctoral candidates will be selected and appointed for a two year training period each year of the award. Committees internal and external to the program will oversee trainee selection and progress, thus insuring fellows take full advantage of the rich, supportive environment and emerge as leaders in urology.

Public Health Relevance

Urologic disease impacts millions of patients with significant losses in quality of life. This training program will build on our history at Northwestern of successfully training leaders in urology by providing fellowships to support the next generation of leaders in urologic sciences

National Institute of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Institutional National Research Service Award (T32)
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Kidney, Urologic and Hematologic Diseases D Subcommittee (DDK)
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Spruance, Victoria Marie
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Northwestern University at Chicago
Schools of Medicine
United States
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Plebanek, Michael P; Bhaumik, Debayan; Bryce, Paul J et al. (2018) Scavenger Receptor Type B1 and Lipoprotein Nanoparticle Inhibit Myeloid-Derived Suppressor Cells. Mol Cancer Ther 17:686-697
Plebanek, Michael P; Angeloni, Nicholas L; Vinokour, Elena et al. (2017) Pre-metastatic cancer exosomes induce immune surveillance by patrolling monocytes at the metastatic niche. Nat Commun 8:1319
Angeloni, Nicholas L; McMahon, Kaylin M; Swaminathan, Suchitra et al. (2016) Pathways for Modulating Exosome Lipids Identified By High-Density Lipoprotein-Like Nanoparticle Binding to Scavenger Receptor Type B-1. Sci Rep 6:22915
Rudick, Charles N; Jiang, Mingchen; Yaggie, Ryan E et al. (2012) O-antigen modulates infection-induced pain states. PLoS One 7:e41273
Rudick, Charles N; Pavlov, Vladimir I; Chen, Michael C et al. (2012) Gender specific pelvic pain severity in neurogenic cystitis. J Urol 187:715-24
Done, Joseph D; Rudick, Charles N; Quick, Marsha L et al. (2012) Role of mast cells in male chronic pelvic pain. J Urol 187:1473-82
Biyashev, Dauren; Veliceasa, Dorina; Topczewski, Jacek et al. (2012) miR-27b controls venous specification and tip cell fate. Blood 119:2679-87
Rudick, Charles N; Billips, Benjamin K; Pavlov, Vladimir I et al. (2010) Host-pathogen interactions mediating pain of urinary tract infection. J Infect Dis 201:1240-9
Aurora, Arin B; Aurora, Aryn B; Biyashev, Dauren et al. (2010) NF-kappaB balances vascular regression and angiogenesis via chromatin remodeling and NFAT displacement. Blood 116:475-84
Rudick, Charles N; Schaeffer, Anthony J; Klumpp, David J (2009) Pharmacologic attenuation of pelvic pain in a murine model of interstitial cystitis. BMC Urol 9:16

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