The purpose of Washington University's Medical Scientist Training Program is to provide in-depth training in the techniques of modern biomedical research and clinical medicine for individuals who wish to pursue careers as physician-scientists in academic settings. Research training is carried out in the interdisciplinary graduate programs of the Department of Biomedical Engineering and the Division of Biology and Biomedical Sciences, and the Departments of Anthropology and Physics. The basic components of the MSTP are: 1) two years of the preclinical medical school curriculum;2) coursework in a biomedically-relevant discipline;3) three or more years of original hypothesis-driven research leading to a doctoral thesis;and 4) 15-24 months of clinical training. The M.D. and Ph.D. degrees are awarded jointly at the successful completion of these components. Upon completion of postgraduate training, MSTP alumni will be prepared to enter the workforce as physician-scientists. The vast majority of alumni will join the faculty of the nation's medical schools, where they will treat patients, teach and conduct cutting-edge research that has relevance to human health and disease. Others will contribute to the biomedical research enterprise from positions in government labs, biotech firms and the pharmaceutical industry. We seek renewal of the National Research Service Award-Medical Scientist (T32 GM07200) to provide critical support for the training of physician-scientists. We propose to appoint 55 students annually to this grant for 36 months of support each. The remainder of the students'training will be supported by funds available to Washington University. Our goal is to graduate 20-25 MSTP students each year over the period of this grant.

Public Health Relevance

Washington University's MSTP trains future physician-scientists for careers in academic medicine, where they treat patients, teach medical students, and conduct cutting-edge research that improves human health and eradicates disease.

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Institutional National Research Service Award (T32)
Project #
3T32GM007200-38S1
Application #
8496594
Study Section
National Institute of General Medical Sciences Initial Review Group (BRT)
Program Officer
Preusch, Peter C
Project Start
1975-07-01
Project End
2015-06-30
Budget Start
2012-07-01
Budget End
2013-06-30
Support Year
38
Fiscal Year
2012
Total Cost
$99,310
Indirect Cost
$4,246
Name
Washington University
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
068552207
City
Saint Louis
State
MO
Country
United States
Zip Code
63130
Ligon, Marianne M; Mysorekar, Indira U (2018) Trans-mission control in the urinary tract: Local cytokine regulation of monocyte proliferation to combat infection. J Leukoc Biol 103:5-7
Barnette, Dustyn A; Davis, Mary A; Dang, Na L et al. (2018) Lamisil (terbinafine) toxicity: Determining pathways to bioactivation through computational and experimental approaches. Biochem Pharmacol 156:10-21
Klein, Roger D; Shu, Qin; Cusumano, Zachary T et al. (2018) Structure-Function Analysis of the Curli Accessory Protein CsgE Defines Surfaces Essential for Coordinating Amyloid Fiber Formation. MBio 9:
Lin, Joseph B; Sene, Abdoulaye; Wiley, Luke A et al. (2018) WNT7A/B promote choroidal neovascularization. Exp Eye Res 174:107-112
Wang, Zhuo A; Li, Lucy X; Doering, Tamara L (2018) Unraveling synthesis of the cryptococcal cell wall and capsule. Glycobiology 28:719-730
Li, Lucy X; Rautengarten, Carsten; Heazlewood, Joshua L et al. (2018) UDP-Glucuronic Acid Transport Is Required for Virulence of Cryptococcus neoformans. MBio 9:
Ban, Norimitsu; Lee, Tae Jun; Sene, Abdoulaye et al. (2018) Disrupted cholesterol metabolism promotes age-related photoreceptor neurodegeneration. J Lipid Res 59:1414-1423
Stopschinski, Barbara E; Holmes, Brandon B; Miller, Gregory M et al. (2018) Specific glycosaminoglycan chain length and sulfation patterns are required for cell uptake of tau versus ?-synuclein and ?-amyloid aggregates. J Biol Chem 293:10826-10840
Verbaro, Daniel J; Sakurai, Nagisa; Kim, Byungil et al. (2018) Cutting Edge: The Histone Methyltransferase G9a Is Required for Silencing of Helper T Lineage-Associated Genes in Proliferating CD8 T Cells. J Immunol 200:3891-3896
Grither, Whitney R; Longmore, Gregory D (2018) Inhibition of tumor-microenvironment interaction and tumor invasion by small-molecule allosteric inhibitor of DDR2 extracellular domain. Proc Natl Acad Sci U S A 115:E7786-E7794

Showing the most recent 10 out of 387 publications