Abstract

The UCSF Graduate Program in Biomedical Sciences is an interdisciplinary program that trains students for research careers investigating the molecular basis of tissue and organ function in health and disease. It offers a novel integrative curriculum, designed specifically for graduate students, which provides a foundation in cell biology, molecular biology, genetics, and biochemistry as applied to research problems in human developmental biology, physiology, and disease. Training is supported by laboratory rotations, journal clubs, and research seminars. The program's faculty consists of 95 members drawn from both basic science and clinical departments. Their research interests are broad, but focused into eight thematic areas: Cancer Biology and Cell Signaling, Genetics and Genomics, Vascular and Cardiac Biology, Developmental and Stem Cell Biology, Immunology, Microbial Pathogenesis and Virology, Neuroscience, and Tissue/Organ Biology and Endocrinology. Trainees are chosen from a national applicant pool, with special effort to include underrepresented minorities. The interdisciplinary spirit of the program reflects the interactive scientific culture at UCSF.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Institutional National Research Service Award (T32)
Project #
5T32GM008568-15
Application #
7642285
Study Section
National Institute of General Medical Sciences Initial Review Group (BRT)
Program Officer
Cole, Alison E
Project Start
1995-07-01
Project End
2010-06-30
Budget Start
2009-07-01
Budget End
2010-06-30
Support Year
15
Fiscal Year
2009
Total Cost
$283,633
Indirect Cost

  Institution

Name
University of California San Francisco
Department
Pathology
Type
Schools of Medicine
DUNS #
094878337
City
San Francisco
State
CA
Country
United States
Zip Code
94143

  Publications

Chitre, Avantika S; Kattah, Michael G; Rosli, Yenny Y et al. (2018) A20 upregulation during treated HIV disease is associated with intestinal epithelial cell recovery and function. PLoS Pathog 14:e1006806
Rana, Manish K; Aloisio, Francesca M; Choi, Changhoon et al. (2018) Formin-dependent TGF-? signaling for epithelial to mesenchymal transition. Mol Biol Cell 29:1465-1475
Mancini, Andrew; Xavier-Magalhães, Ana; Woods, Wendy S et al. (2018) Disruption of the ?1L Isoform of GABP Reverses Glioblastoma Replicative Immortality in a TERT Promoter Mutation-Dependent Manner. Cancer Cell 34:513-528.e8
Emmerson, Elaine; May, Alison J; Berthoin, Lionel et al. (2018) Salivary glands regenerate after radiation injury through SOX2-mediated secretory cell replacement. EMBO Mol Med 10:
Donnella, Hayley J; Webber, James T; Levin, Rebecca S et al. (2018) Kinome rewiring reveals AURKA limits PI3K-pathway inhibitor efficacy in breast cancer. Nat Chem Biol 14:768-777
Ye, Wenlei; Han, Tina W; Nassar, Layla M et al. (2018) Phosphatidylinositol-(4, 5)-bisphosphate regulates calcium gating of small-conductance cation channel TMEM16F. Proc Natl Acad Sci U S A 115:E1667-E1674
Chang, Roger; Eriksen, Jacob; Edwards, Robert H (2018) The dual role of chloride in synaptic vesicle glutamate transport. Elife 7:
Saiki, Julie P; Cao, Hongbin; Van Wassenhove, Lauren D et al. (2018) Aldehyde dehydrogenase 3A1 activation prevents radiation-induced xerostomia by protecting salivary stem cells from toxic aldehydes. Proc Natl Acad Sci U S A 115:6279-6284
Durack, Juliana; Kimes, Nikole E; Lin, Din L et al. (2018) Delayed gut microbiota development in high-risk for asthma infants is temporarily modifiable by Lactobacillus supplementation. Nat Commun 9:707
Smith, Lucas K; White 3rd, Charles W; Villeda, Saul A (2018) The systemic environment: at the interface of aging and adult neurogenesis. Cell Tissue Res 371:105-113

Showing the most recent 10 out of 90 publications