Abstract

The Program in Molecular Biology and Biotechnology proposes to create a training program in Cell and Molecular Biology. This program will train outstanding students in a broad interdisciplinary program covering all aspects of Cell and Molecular Biology. Participating faculty in the program will be drawn from the basic science departments of the School of Medicine, the Department of Biology from the School of Arts and Sciences and from the Department of Medicine. The students will receive their Ph.D. degrees in one of the participating departments or in the Curriculum in Genetics and Molecular Biology. A unified curriculum is described which will ensure that the students receive appropriate training. We are requesting support for recruitment of graduate students into this program. We are also requesting support for student travel and supplies for their research.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Institutional National Research Service Award (T32)
Project #
5T32GM008581-04
Application #
2872592
Study Section
Special Emphasis Panel (ZGM1-CMB-6)
Project Start
1996-07-01
Project End
2001-06-30
Budget Start
1999-07-01
Budget End
2000-06-30
Support Year
4
Fiscal Year
1999
Total Cost
Indirect Cost

  Institution

Name
University of North Carolina Chapel Hill
Department
Biochemistry
Type
Schools of Medicine
DUNS #
078861598
City
Chapel Hill
State
NC
Country
United States
Zip Code
27599

  Publications

Perkowski, Ellen Foot; Miller, Brittany K; McCann, Jessica R et al. (2016) An orphaned Mce-associated membrane protein of Mycobacterium tuberculosis is a virulence factor that stabilizes Mce transporters. Mol Microbiol 100:90-107
Washington, Erica J; Mukhtar, M Shahid; Finkel, Omri M et al. (2016) Pseudomonas syringae type III effector HopAF1 suppresses plant immunity by targeting methionine recycling to block ethylene induction. Proc Natl Acad Sci U S A 113:E3577-86
Watson, Leah J; Rossi, Guendalina; Brennwald, Patrick (2014) Quantitative analysis of membrane trafficking in regulation of Cdc42 polarity. Traffic 15:1330-43
McCann, Jessica R; McDonough, Justin A; Sullivan, Jonathan Tabb et al. (2011) Genome-wide identification of Mycobacterium tuberculosis exported proteins with roles in intracellular growth. J Bacteriol 193:854-61
Johnson, Søren M; Torrice, Chad D; Bell, Jessica F et al. (2010) Mitigation of hematologic radiation toxicity in mice through pharmacological quiescence induced by CDK4/6 inhibition. J Clin Invest 120:2528-36
Alan, Jamie K; Berzat, Anastacia C; Dewar, Brian J et al. (2010) Regulation of the Rho family small GTPase Wrch-1/RhoU by C-terminal tyrosine phosphorylation requires Src. Mol Cell Biol 30:4324-38
Zimmerman, Eric I; Dollins, Claudia M; Crawford, Melissa et al. (2010) Lyn kinase-dependent regulation of miR181 and myeloid cell leukemia-1 expression: implications for drug resistance in myelogenous leukemia. Mol Pharmacol 78:811-7
Sullivan, Kelly D; Mullen, Thomas E; Marzluff, William F et al. (2009) Knockdown of SLBP results in nuclear retention of histone mRNA. RNA 15:459-72
Douglas, Peter M; Summers, Daniel W; Ren, Hong-Yu et al. (2009) Reciprocal efficiency of RNQ1 and polyglutamine detoxification in the cytosol and nucleus. Mol Biol Cell 20:4162-73
Brady, Donita C; Alan, Jamie K; Madigan, James P et al. (2009) The transforming Rho family GTPase Wrch-1 disrupts epithelial cell tight junctions and epithelial morphogenesis. Mol Cell Biol 29:1035-49

Showing the most recent 10 out of 26 publications