The long-term objective of the T32 UCLA Interdepartmental Clinical Pharmacology Postdoctoral Training Program (ICPTP) is to produce clinical pharmacologists who have expertise in conceptualizing and implementing hypothesis driven, data based clinical pharmacology research;are competent clinically to achieve therapeutics of the highest quality;and are motivated to educate future clinical pharmacologists. The benchmarks of this successful program will be progress in clinical pharmacology research, improved therapeutic outcomes and decreased complication rates, all contributing to increased efficiency of the health care system. The diversity of the UCLA ICPTP has been confirmed both through the association of the David Geffen School of Medicine at UCLA with the Charles Drew University of Medicine and Science and by the specialties of the trainees, who have been MD or MD/PhD junior faculty with primary appointments in Anesthesiology/Critical Care Medicine, internal Medicine (Gastroenterology, Pulmonary, (Allergy/Immunology), Neurology, Obstetrics and Gynecology, Otolaryngology (Head and Neck Surgery), Pediatrics (Gastroenterology, Liver Transplantation, Immunotherapy, Pediatric Endocrinology), Psychiatry and Surgery (Liver Transplantation). This association and breadth of trainee areas of expertise broaden and enrich the T32 UCLA ICPTP curricular experience.

Public Health Relevance

of the UCLA T32 Interdepartmental Clinical Pharmacology Postdoctoral Research Training Program resides in the outcomes or current activities of its graduates, the majority of whom are academicians. The clinical pharmacology skills of ICPTP alumnae translate to their activities as researchers, educators and clinicians, who serve as a nucleus to educate future clinical pharmacologists in diverse specialties, potentially resulting in declining medical errors in practice, hospitals and industry.

National Institute of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
Institutional National Research Service Award (T32)
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Special Emphasis Panel (ZGM1-BRT-5 (PD))
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Okita, Richard T
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University of California Los Angeles
Internal Medicine/Medicine
Schools of Medicine
Los Angeles
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Calkins, Kara L; DeBarber, Andrea; Steiner, Robert D et al. (2017) Intravenous Fish Oil and Pediatric Intestinal Failure-Associated Liver Disease: Changes in Plasma Phytosterols, Cytokines, and Bile Acids and Erythrocyte Fatty Acids. JPEN J Parenter Enteral Nutr :148607117709196
Calkins, Kara L; Havranek, Thomas; Kelley-Quon, Lorraine I et al. (2017) Low-Dose Parenteral Soybean Oil for the Prevention of Parenteral Nutrition-Associated Liver Disease in Neonates With Gastrointestinal Disorders. JPEN J Parenter Enteral Nutr 41:404-411
Levit, Orly L; Calkins, Kara L; Gibson, L Caroline et al. (2016) Low-Dose Intravenous Soybean Oil Emulsion for Prevention of Cholestasis in Preterm Neonates. JPEN J Parenter Enteral Nutr 40:374-82
Xia, Mingcan; Viera-Hutchins, Loida; Garcia-Lloret, Maria et al. (2015) Vehicular exhaust particles promote allergic airway inflammation through an aryl hydrocarbon receptor-notch signaling cascade. J Allergy Clin Immunol 136:441-53
Calkins, Kara L; Venick, Robert S; Devaskar, Sherin U (2014) Complications associated with parenteral nutrition in the neonate. Clin Perinatol 41:331-45
Calkins, Kara; Lowe, Allison; Shew, Stephen B et al. (2013) Short-term intravenous fish oil and pediatric intestinal failure associated liver disease: 3-year follow-up on liver function and nutrition. J Pediatr Surg 48:228-32
Balan, Irina S; Saladino, Andrew J; Aarabi, Bizhan et al. (2013) Cellular alterations in human traumatic brain injury: changes in mitochondrial morphology reflect regional levels of injury severity. J Neurotrauma 30:367-81
Kristian, Tibor; Balan, Irina; Schuh, Rosemary et al. (2011) Mitochondrial dysfunction and nicotinamide dinucleotide catabolism as mechanisms of cell death and promising targets for neuroprotection. J Neurosci Res 89:1946-55
Hoang, Phuong T; Park, Patricia; Cobb, Laura J et al. (2010) The neurosurvival factor Humanin inhibits beta-cell apoptosis via signal transducer and activator of transcription 3 activation and delays and ameliorates diabetes in nonobese diabetic mice. Metabolism 59:343-9
Balan, Irina S; Fiskum, Gary; Kristian, Tibor (2010) Visualization and quantification of NAD(H) in brain sections by a novel histo-enzymatic nitrotetrazolium blue staining technique. Brain Res 1316:112-9