Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Institutional National Research Service Award (T32)
Project #
5T32HL007470-07
Application #
3541083
Study Section
Research Manpower Review Committee (MR)
Project Start
1980-07-01
Project End
1990-06-30
Budget Start
1986-07-01
Budget End
1987-06-30
Support Year
7
Fiscal Year
1986
Total Cost
Indirect Cost
Name
University of North Carolina Chapel Hill
Department
Type
Schools of Medicine
DUNS #
078861598
City
Chapel Hill
State
NC
Country
United States
Zip Code
27599
DiGiusto, David L; Stan, Rodica; Krishnan, Amrita et al. (2013) Development of hematopoietic stem cell based gene therapy for HIV-1 infection: considerations for proof of concept studies and translation to standard medical practice. Viruses 5:2898-919
Zhou, Jiehua; Rossi, John J (2012) Therapeutic potential of aptamer-siRNA conjugates for treatment of HIV-1. BioDrugs 26:393-400
Burnett, John C; Rossi, John J (2012) RNA-based therapeutics: current progress and future prospects. Chem Biol 19:60-71
Aagaard, Lars; Bjerregaard, Bolette; Kjeldbjerg, Anders L et al. (2012) Silencing of endogenous envelope genes in human choriocarcinoma cells shows that envPb1 is involved in heterotypic cell fusions. J Gen Virol 93:1696-9
Sun, Guihua; Li, Haitang; Wu, Xiwei et al. (2012) Interplay between HIV-1 infection and host microRNAs. Nucleic Acids Res 40:2181-96
Neff, Charles Preston; Zhou, Jiehua; Remling, Leila et al. (2011) An aptamer-siRNA chimera suppresses HIV-1 viral loads and protects from helper CD4(+) T cell decline in humanized mice. Sci Transl Med 3:66ra6
Scherer, Lisa J; Rossi, John J (2011) Ex vivo gene therapy for HIV-1 treatment. Hum Mol Genet 20:R100-7
Zhou, Jiehua; Li, Haitang; Zhang, Jane et al. (2011) Development of cell-type specific anti-HIV gp120 aptamers for siRNA delivery. J Vis Exp :
Zhou, J; Rossi, J J (2011) Current progress in the development of RNAi-based therapeutics for HIV-1. Gene Ther 18:1134-8
Zhou, Jiehua; Rossi, John J (2011) Cell-specific aptamer-mediated targeted drug delivery. Oligonucleotides 21:1-10

Showing the most recent 10 out of 39 publications