The Integrated Graduate Program in Neuroscience at UTHSCSA provides training in a range of neuroscientific research areas and approaches, from molecular, cellular, and neurochemical to systems, behavioral and clinical neuroscience. With 30 training faculty drawn from the mentoring faculty in the Neuroscience Program within the Integrated Biomedical Sciences Graduate Program (IBMS) at UTHSCSA, this Training Program offers a course of study tailored to the individual needs and interests of students who come to us from a variety of backgrounds in the basic biological sciences, including biology, biochemistry, chemistry, molecular biology, psychology and neuroscience. An interactive and collegial community of educators and researchers creates a challenging yet supportive environment within which our students can develop into successful neuroscientists. Program Goals are to provide our students: I) a curriculum that gives them a broad foundation of fundamental concepts in Neuroscience; II) skills and knowledge necessary to conduct high-quality Neuroscience research; and III) training in ethical behavior and responsible conduct, and professional skills that will prepare them for successful careers as independent neuroscientists. A set of 8 Student Learning Objectives that service these goals form the basis for a program evaluation and monitoring system that informs ongoing evolution of our program, including changes, additions and improvements to curriculum, professional development and enrichment activities, and other elements of the program. The progress of our students is facilitated and monitored by a robust administrative and organizational structure, and experienced program leadership. Students enter the IBMS, and are fully supported by the graduate school during their first year. In the first semester they take a common biomedical sciences course and conduct lab rotations. They join a lab and begin the Neuroscience curriculum in the spring semester. The students to be supported by this T32 training grant are selected at the end of the first summer, to be supported during their second year of study, during which they complete the core Neuroscience course curriculum, conduct a Clinical Practicum in Neuroscience, develop their research project, and engage in several enrichment and professional development activities before completing the Qualifying Exam at the end of year 2. In the year following support, students present their dissertation proposal and submit individual fellowship applications. Other advanced-stage T32s on our campus may support post-QE Neuroscience students working in relevant areas while they navigate the fellowship submission and revision process. Our program has been successful, with a nearly 90% retention and completion rate, and essentially 100% of students who completed their degree proceeded to research-intensive or research-related positions. We also have a strong history of successful outcomes training students from under-represented populations, while maintaining national competitiveness. Renewed funding of this training grant will continue the growth and development of our program, and enhance our ability to train our students for the challenges of the future.

Public Health Relevance

The Integrated Graduate Program in Neuroscience at the University of Texas Health Science Center at San Antonio provides training in many areas of expertise from molecular to behavioral neuroscience, in a biomedical research environment that fosters a unique exposure to clinical and translational neuroscience. We provide a program of coursework, mentored laboratory research, and professional enrichment activities tailored to the individual interests and needs of our students, with a history of successful outcomes training motivated and talented students from under-represented populations, and sustaining competitiveness on a national scale. Renewed funding of this training grant will continue the growth and development of our program, and enhance our ability to launch our students into successful careers as neuroscientists, equipped to address complex challenges, both present and future, in our field.

Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
Institutional National Research Service Award (T32)
Project #
5T32NS082145-07
Application #
9705909
Study Section
Special Emphasis Panel (ZNS1)
Program Officer
Weigand, Letitia Alexis
Project Start
2013-07-01
Project End
2023-06-30
Budget Start
2019-07-01
Budget End
2020-06-30
Support Year
7
Fiscal Year
2019
Total Cost
Indirect Cost
Name
University of Texas Health Science Center
Department
Pharmacology
Type
Schools of Medicine
DUNS #
800772162
City
San Antonio
State
TX
Country
United States
Zip Code
78229
Fucich, Elizabeth A; Paredes, Denisse; Saunders, Madeleine O et al. (2018) Activity in the Ventral Medial Prefrontal Cortex Is Necessary for the Therapeutic Effects of Extinction in Rats. J Neurosci 38:1408-1417
Fucich, Elizabeth A; Morilak, David A (2018) Shock-probe Defensive Burying Test to Measure Active versus Passive Coping Style in Response to an Aversive Stimulus in Rats. Bio Protoc 8:
Girotti, Milena; Adler, Samantha M; Bulin, Sarah E et al. (2018) Prefrontal cortex executive processes affected by stress in health and disease. Prog Neuropsychopharmacol Biol Psychiatry 85:161-179
Garrison, Allison M; Parrott, Jennifer M; Tuñon, Arnulfo et al. (2018) Kynurenine pathway metabolic balance influences microglia activity: Targeting kynurenine monooxygenase to dampen neuroinflammation. Psychoneuroendocrinology 94:1-10
Jacobs, Blaine A; Pando, Miryam M; Jennings, Elaine et al. (2018) Allosterism within ? Opioid-? Opioid Receptor Heteromers in Peripheral Sensory Neurons: Regulation of ? Opioid Agonist Efficacy. Mol Pharmacol 93:376-386
Avelar, Alicia J; Cao, Jianjing; Newman, Amy Hauck et al. (2017) Atypical dopamine transporter inhibitors R-modafinil and JHW 007 differentially affect D2 autoreceptor neurotransmission and the firing rate of midbrain dopamine neurons. Neuropharmacology 123:410-419
Ye, Liang; Haroon, Mateen A; Salinas, Angelica et al. (2017) Comparison of GCaMP3 and GCaMP6f for studying astrocyte Ca2+ dynamics in the awake mouse brain. PLoS One 12:e0181113
Sullivan, Laura C; Chavera, Teresa A; Gao, Xiaoli et al. (2017) Regulation of ? Opioid Receptor-Mediated Signaling and Antinociception in Peripheral Sensory Neurons by Arachidonic Acid-Dependent 12/15-Lipoxygenase Metabolites. J Pharmacol Exp Ther 362:200-209
Fucich, Elizabeth A; Paredes, Denisse; Morilak, David A (2016) Therapeutic Effects of Extinction Learning as a Model of Exposure Therapy in Rats. Neuropsychopharmacology 41:3092-3102
Solano Fonseca, Rene; Mahesula, Swetha; Apple, Deana M et al. (2016) Neurogenic Niche Microglia Undergo Positional Remodeling and Progressive Activation Contributing to Age-Associated Reductions in Neurogenesis. Stem Cells Dev 25:542-55

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