Research at an early stage of medical education is the best predictor of a future career in research. The College of Physicians &Surgeons of Columbia is especially strong in research focusing on the basic and applied features of diabetes, kidney and endocrinologic diseases. Investigation of the health issues dealing with the mandate of NIDDK requires preparations for the next generation of investigators and this application aims to introduce our medical students to research in these fields mentored by exceptional faculty with proven track record of excellence in research and funding. The curriculum at P &S has changed such that every student is now required to produce a scholarly effort and this proposal will support students performing research either during the summer months between the 1st and 2nd years or later. Students at P&S have traditionally been active in research and this application will provide them with a structured program that includes the research as well as a series of seminars covering topics in modern biomedical research. In addition they will be required to attend a series of lectures in the Responsible Conduct of Research. The Program Director will be assisted in managing the Program by an External and an Internal Advisory Committees. Applying students will be chosen by a Recruitment and Admission Committee and their progress in research will be followed by a Mentoring Committee. Finally, after they complete their research they will be advised by a Career Development committee that will aid them in making important career decisions. Recruitment of under-represented minorities, among mentors as well as students, is strongly supported by an ongoing commitment of the College and by targeted efforts of the Program.

Public Health Relevance

The burden of diabetes and other hormonal diseases, kidney and gastro-intestinal and liver diseases represent some of the major health problems in the US and the world at large. The mandate of NIDDK is to reduce this burden through innovative research. This proposal aims at supporting the research of medical students in these areas through working in laboratories of successful scientists whose aim is to investigate the nature and treatment of these diseases. Early exposure to exciting research is the best inducement for young physicians to enter a career of investigation and thus provide the next generation of researchers

National Institute of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NRSA Short -Term Research Training (T35)
Project #
Application #
Study Section
Diabetes, Endocrinology and Metabolic Diseases B Subcommittee (DDK)
Program Officer
Podskalny, Judith M,
Project Start
Project End
Budget Start
Budget End
Support Year
Fiscal Year
Total Cost
Indirect Cost
Columbia University (N.Y.)
Internal Medicine/Medicine
Schools of Medicine
New York
United States
Zip Code
Kazzi, Brigitte; Lederer, David; Arteaga-Solis, Emilio et al. (2018) Recurrent diffuse lung disease due to surfactant protein C deficiency. Respir Med Case Rep 25:91-95
Mohan, Sumit; Campenot, Eric; Chiles, Mariana C et al. (2017) Association between Reperfusion Renal Allograft Biopsy Findings and Transplant Outcomes. J Am Soc Nephrol 28:3109-3117
Park, Howard Y; Matsumoto, Hiroko; Feinberg, Nicholas et al. (2017) The Classification for Early-onset Scoliosis (C-EOS) Correlates With the Speed of Vertical Expandable Prosthetic Titanium Rib (VEPTR) Proximal Anchor Failure. J Pediatr Orthop 37:381-386
Lascano, Danny; Pak, Jamie S; Kates, Max et al. (2015) Validation of a frailty index in patients undergoing curative surgery for urologic malignancy and comparison with other risk stratification tools. Urol Oncol 33:426.e1-426.e12
Kelso, Catherine M; Watanabe, Hirobumi; Wazen, Joseph M et al. (2015) Microperforations significantly enhance diffusion across round window membrane. Otol Neurotol 36:694-700
Lumish, Heidi S; Wynn, Julia; Devinsky, Orrin et al. (2015) Brief Report: SETD2 Mutation in a Child with Autism, Intellectual Disabilities and Epilepsy. J Autism Dev Disord 45:3764-70
Najjar, Marc; Yerebakan, Halit; Sorabella, Robert A et al. (2015) Acute kidney injury following surgical aortic valve replacement. J Card Surg 30:631-9
Lumish, Heidi S; Yang, Yaping; Xia, Fan et al. (2014) The Expanding MEGDEL Phenotype: Optic Nerve Atrophy, Microcephaly, and Myoclonic Epilepsy in a Child with SERAC1 Mutations. JIMD Rep 16:75-9
Mohan, Sumit; Gu, Sue; Parikh, Amay et al. (2013) Prevalence of hyponatremia and association with mortality: results from NHANES. Am J Med 126:1127-37.e1