Research during the early years of medical education trains medical students in quantitative reasoning, and scientific literacy as well as expose them to a mentors who have devoted their careers to investigation. It thus sharpens their understanding of the processes by which the practice of medicine develops and improves as well as stimulating their interests in research careers. The curriculum at the College of Physicians and Surgeons of Columbia University now requires that all medical students produce a ?Scholarly Effort? before graduation expanding our pool of applicants. Research in basic and clinical aspects of Diabetes, Endocrinology, Obesity, Kidney, Urology and Digestive Diseases is particularly strong at our medical school with more than 60 investigators having current RO1 grants. Over the past 4 years, 70 of our students applied each year to enter the T35 training program. While we had initially asked for an annual support of 8-12 students, there were many more qualified applicants and through re-budgeting of our non-training funds we were able to fund 52 students working in these areas (~13/year). The students attended weekly seminars in important topics including career development and the responsible conduct of research. In addition, we hosted a weekly journal club specific for NIDDK trainees where mentors discussed their current research using their publications in high impact journals. We acted as a regional center for medical student research in NIDDK funded fields recruiting 5 additional students who worked with our mentors. The outcomes have exceeded our expectations, 10 of our students over this short period decided to dedicate an additional year of research to their projects; 7 of them had published peer-reviewed papers and 14 presented their work at national and international meetings. Building on our success, we have recruited 35 NIDDK funded mentors to train the future group of medical students. The Program will be supervised by a recruitment and admission committee that will choose the students from the applicant pool, a committee that follows their progress and an internal advisory committee that helps the PI/PD in running the program. Finally, a career development committee will aid the students in making important career decision as they progress through medical school. Recruitment of under-represented minorities among mentors and students is strongly supported by leadership of the College and University and by targeted efforts of this Program.

Public Health Relevance

The burden of diabetes and other hormonal diseases, kidney and gastro-intestinal and liver diseases represent some of the major health problems in the US and the world at large. The mandate of NIDDK is to reduce this burden through innovative research. We have supported 52 students in the past 4 years in research by medical students in laboratories of successful scientists who investigate the nature and treatment of these diseases. Early exposure to exciting research is the best inducement for young physicians to enter a career of investigation and thus provide the next generation of researchers

Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
NRSA Short -Term Research Training (T35)
Project #
5T35DK093430-07
Application #
9471381
Study Section
Kidney, Urologic and Hematologic Diseases D Subcommittee (DDK)
Program Officer
Castle, Arthur
Project Start
2012-03-15
Project End
2022-04-30
Budget Start
2018-05-01
Budget End
2019-04-30
Support Year
7
Fiscal Year
2018
Total Cost
Indirect Cost
Name
Columbia University (N.Y.)
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
621889815
City
New York
State
NY
Country
United States
Zip Code
10032
Kazzi, Brigitte; Lederer, David; Arteaga-Solis, Emilio et al. (2018) Recurrent diffuse lung disease due to surfactant protein C deficiency. Respir Med Case Rep 25:91-95
Mohan, Sumit; Campenot, Eric; Chiles, Mariana C et al. (2017) Association between Reperfusion Renal Allograft Biopsy Findings and Transplant Outcomes. J Am Soc Nephrol 28:3109-3117
Park, Howard Y; Matsumoto, Hiroko; Feinberg, Nicholas et al. (2017) The Classification for Early-onset Scoliosis (C-EOS) Correlates With the Speed of Vertical Expandable Prosthetic Titanium Rib (VEPTR) Proximal Anchor Failure. J Pediatr Orthop 37:381-386
Lascano, Danny; Pak, Jamie S; Kates, Max et al. (2015) Validation of a frailty index in patients undergoing curative surgery for urologic malignancy and comparison with other risk stratification tools. Urol Oncol 33:426.e1-426.e12
Kelso, Catherine M; Watanabe, Hirobumi; Wazen, Joseph M et al. (2015) Microperforations significantly enhance diffusion across round window membrane. Otol Neurotol 36:694-700
Lumish, Heidi S; Wynn, Julia; Devinsky, Orrin et al. (2015) Brief Report: SETD2 Mutation in a Child with Autism, Intellectual Disabilities and Epilepsy. J Autism Dev Disord 45:3764-70
Najjar, Marc; Yerebakan, Halit; Sorabella, Robert A et al. (2015) Acute kidney injury following surgical aortic valve replacement. J Card Surg 30:631-9
Lumish, Heidi S; Yang, Yaping; Xia, Fan et al. (2014) The Expanding MEGDEL Phenotype: Optic Nerve Atrophy, Microcephaly, and Myoclonic Epilepsy in a Child with SERAC1 Mutations. JIMD Rep 16:75-9
Mohan, Sumit; Gu, Sue; Parikh, Amay et al. (2013) Prevalence of hyponatremia and association with mortality: results from NHANES. Am J Med 126:1127-37.e1