Objectives, rationale and program design. For the last nine years, The Institute of Translational Health Sciences' (ITHS) TL1 training program has prepared predoctoral investigators from across the University of Washington (UW) Health Sciences Schools with the skills and knowledge that supports translational science careers.
The Specific Aim of this application is to create a cross-disciplinary community of predoctoral scientists and provide them with methodologic training, career development opportunities, and team science skills to function effectively within translational science teams. Program objectives are met through a mentored research component and individualized structured coursework that includes core courses, enhanced experiential components, and courses targeting multidisciplinary team science. Trainees' mentored research projects are related to dissertation research or fulfill the research requirement for the graduate degree for those supplementing professional degree training. No other UW institutional T32 program draws trainees from across disciplines, provides training on specific translational research competencies with an emphasis team science, and offers interdisciplinary learning through the ongoing and significant trainee interactions. Program research training, key activities, and scientific disciplines: Core coursework includes biomedical research integrity, design, and methods of translational research, translational research competencies, conduct of interdisciplinary research, and multidisciplinary communication and interactions. Additional courses in methods relevant to translational science are required such as biostatistics, epidemiologic methods, or clinical trial design, but the exact program of study is individualized per trainee needs and goals. An outstanding pool of mentors, with primary appointments in 21 departments across eight schools, supports our TL1 trainees. Levels and duration of training: ITHS' 12-month, predoctoral training program is intended for graduate students in pre-licensure professional health sciences programs or students in PhD programs of clinical fields such as nursing, pharmacy, public health, social work, or other related fields (e.g., bioengineering). Projected number of trainees, levels of experience, and program outcomes: TL1 accepts 20 trainees from the health sciences (i.e., Nursing, Pharmacy, Dentistry, Public Health, Social Work, and Medicine) and the Colleges of Engineering and Department of Speech and Hearing Sciences. Trainees must demonstrate interest in translational science and be able to identify/develop a specific translational science proposal with a mentor. Differences in preparation among the multidisciplinary trainees are expected and individualized coursework helps to meet basic requirements and/or round out prior training. Trainees must complete all course requirements, their research project, related presentations and publications, and an assessment of competency in translational and team science skills.

Agency
National Institute of Health (NIH)
Institute
National Center for Advancing Translational Sciences (NCATS)
Type
Linked Training Award (TL1)
Project #
5TL1TR002318-04
Application #
9878946
Study Section
Special Emphasis Panel (ZTR1)
Program Officer
Zhang, Xinzhi
Project Start
2017-06-01
Project End
2022-02-28
Budget Start
2020-03-01
Budget End
2021-02-28
Support Year
4
Fiscal Year
2020
Total Cost
Indirect Cost
Name
University of Washington
Department
Type
Schools of Medicine
DUNS #
605799469
City
Seattle
State
WA
Country
United States
Zip Code
98195
Rebbe, Rebecca; Mienko, Joseph A; Brown, Emily et al. (2018) Child protection reports and removals of infants diagnosed with prenatal substance exposure. Child Abuse Negl 88:28-36
Vogel, Mia T; Abu-Rish Blakeney, Erin; Willgerodt, Mayumi A et al. (2018) Interprofessional education and practice guide: interprofessional team writing to promote dissemination of interprofessional education scholarship and products. J Interprof Care :1-8
Chambers, Laura C; Manhart, Lisa E; Katz, David A et al. (2018) Comparison of Algorithms to Triage Patients to Express Care in a Sexually Transmitted Disease Clinic. Sex Transm Dis 45:696-702
Wong, Timothy; Wang, Zhican; Chapron, Brian D et al. (2018) Polymorphic Human Sulfotransferase 2A1 Mediates the Formation of 25-Hydroxyvitamin D3-3-O-Sulfate, a Major Circulating Vitamin D Metabolite in Humans. Drug Metab Dispos 46:367-379
Au, Nicholas T; Ryman, Tove; Rettie, Allan E et al. (2018) Dietary Vitamin K and Association with Hepatic Vitamin K Status in a Yup'ik Study Population from Southwestern Alaska. Mol Nutr Food Res 62:
Beima-Sofie, Kristin; Wamalwa, Dalton; Maleche-Obimbo, Elizabeth et al. (2018) Toll-like receptor 9 polymorphism is associated with increased Epstein-Barr virus and Cytomegalovirus acquisition in HIV-exposed infants. AIDS 32:267-270
Richards, Claire A; Starks, Helene; O'Connor, M Rebecca et al. (2018) Physicians Perceptions of Shared Decision-Making in Neonatal and Pediatric Critical Care. Am J Hosp Palliat Care 35:669-676
Feuerstein, Julie L; Olswang, Lesley B; Greenslade, Kathryn J et al. (2018) Implementation Research: Embracing Practitioners' Views. J Speech Lang Hear Res 61:645-657
Rosenberg, Alexander B; Roco, Charles M; Muscat, Richard A et al. (2018) Single-cell profiling of the developing mouse brain and spinal cord with split-pool barcoding. Science 360:176-182
Evangelista, Eric A; Lemaitre, Rozenn N; Sotoodehnia, Nona et al. (2018) CYP2J2 Expression in Adult Ventricular Myocytes Protects Against Reactive Oxygen Species Toxicity. Drug Metab Dispos 46:380-386

Showing the most recent 10 out of 58 publications