Immune Control and Evadion during Acute HCV Infection

Lauer, Georg Michael

Abstract

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Institute of Allergy and Infectious Diseases (NIAID)
• Type: Research Project--Cooperative Agreements (U01)
• Project #: 1U01AI131314-01
• Application #: 9325251
• Study Section: Special Emphasis Panel (ZAI1-MFH-M (J1))
• Program Officer: Koshy, Rajen
• Project Start: 2016-08-20
• Project End: 2021-07-31
• Budget Start: 2016-08-20
• Budget End: 2017-07-31
• Support Year: 1
• Fiscal Year: 2016
• Total Cost: $276,000
• Indirect Cost: $114,596

Institution

• Name: Massachusetts General Hospital
• Type: Other Domestic Higher Education
• DUNS #: 073130411
• City: Boston
• State: MA
• Country: United States
• Zip Code: 02114

Publications

Torres-Cornejo, Almudena; Lauer, Georg M (2017) Hurdles to the Development of Effective HBV Immunotherapies and HCV Vaccines. Pathog Immun 2:102-125

Vergara, C; Thio, C; Latanich, R et al. (2017) Genetic basis for variation in plasma IL-18 levels in persons with chronic hepatitis C virus and human immunodeficiency virus-1 infections. Genes Immun 18:82-87

Wolski, David; Foote, Peter K; Chen, Diana Y et al. (2017) Early Transcriptional Divergence Marks Virus-Specific Primary Human CD8+ T Cells in Chronic versus Acute Infection. Immunity 47:648-663.e8

Rodrigo, Chaturaka; Walker, Melanie R; Leung, Preston et al. (2017) Limited naturally occurring escape in broadly neutralizing antibody epitopes in hepatitis C glycoprotein E2 and constrained sequence usage in acute infection. Infect Genet Evol 49:88-96