Abstract

The major goal of this proposal is the establishment of an inter-institutional Network for automated flow cytometry research in the diagnosis and treatment of urinary bladder cancer. This includes: (1) Establish methodologies and collaborative procedures to be used by the Network; (2) Utilize multidimensional slit-scan flow cytometry, conventional zero resolution flow cytometry, and static cell cytofluorometry instrumentation in support of Network studies; (3) Continue studies on bladder irrigation specimen collection, preparation and staining in collaboration with Network laboratories; (4) Expand specimen collection Network to accommodate proposed Network studies; (5) Determine the feasibility and methodology for using exfoliated cells present in voided urine in the diagnosis and treatment of urinary bladder carcinoma; (6) Establish Network studies directed toward following patients undergoing treatment, as well as monitoring high-risk populations for detection of bladder cancer; (7) Continue existing funded bladder cancer grant research in conjunction with proposed Network studies; and (8) Collaborate with Network laboratories towards the goal of establishing the clinical utility of automated flow cytometry in the diagnosis and treatment of urinary bladder cancer.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project--Cooperative Agreements (U01)
Project #
3U01CA041031-03S1
Application #
3548778
Study Section
(SRC)
Project Start
1985-09-30
Project End
1989-09-30
Budget Start
1987-09-01
Budget End
1989-09-30
Support Year
3
Fiscal Year
1988
Total Cost
Indirect Cost

  Institution

Name
University of Rochester
Department
Type
School of Medicine & Dentistry
DUNS #
208469486
City
Rochester
State
NY
Country
United States
Zip Code
14627