|
Spiro, T P; Liu, L; Majka, S et al. (2001) Temozolomide: the effect of once- and twice-a-day dosing on tumor tissue levels of the DNA repair protein O(6)-alkylguanine-DNA-alkyltransferase. Clin Cancer Res 7:2309-17
|
|
Koc, O N; Allay, J A; Lee, K et al. (1996) Transfer of drug resistance genes into hematopoietic progenitors to improve chemotherapy tolerance. Semin Oncol 23:46-65
|
|
Liu, L; Lee, K; Wasan, E et al. (1996) Differential sensitivity of human and mouse alkyltransferase to O6-benzylguanine using a transgenic model. Cancer Res 56:1880-5
|
|
Gerson, S L; Phillips, W; Kastan, M et al. (1996) Human CD34+ hematopoietic progenitors have low, cytokine-unresponsive O6-alkylguanine-DNA alkyltransferase and are sensitive to O6-benzylguanine plus BCNU. Blood 88:1649-55
|
|
Belanich, M; Randall, T; Pastor, M A et al. (1996) Intracellular Localization and intercellular heterogeneity of the human DNA repair protein O(6)-methylguanine-DNA methyltransferase. Cancer Chemother Pharmacol 37:547-55
|
|
Berg, S L; Gerson, S L; Godwin, K et al. (1995) Plasma and cerebrospinal fluid pharmacokinetics of O6-benzylguanine and time course of peripheral blood mononuclear cell O6-methylguanine-DNA methyltransferase inhibition in the nonhuman primate. Cancer Res 55:4606-10
|
|
Gerson, S L; Allay, E; Vitantonio, K et al. (1995) Determinants of O6-alkylguanine-DNA alkyltransferase activity in human colon cancer. Clin Cancer Res 1:519-25
|
|
Gerson, S L; Willson, J K (1995) O6-alkylguanine-DNA alkyltransferase. A target for the modulation of drug resistance. Hematol Oncol Clin North Am 9:431-50
|
|
Gerson, S L; Berger, S J; Varnes, M E et al. (1994) Combined depletion of O6-alkylguanine-DNA alkyltransferase and glutathione to modulate nitrosourea resistance in breast cancer. Biochem Pharmacol 48:543-8
|
