The overall goal of this study is to develop a monitoring system and to evaluate the effectiveness of a community-based intervention designed to reduce the incidence and spread of HIV/AIDS and needle use-among injecting drug abusers, their sexual partners and individuals at demonstrated risk for injecting drug use not in treatment. The study will be conducted in a low-prevalence area by the University of Kentucky, in collaboration with the Lexington Community Action Council and the Louisville Volunteers of America. The specific study aims are to: (1) Establish a monitoring system (N = 2928); (2) Complete a formative pilot study to refine the interventions for rural and Appalachians during the initial six months; (3) Recruit 1066 injecting drug users and sex partners into two levels of the interventions; (4) Randomly assign 533 subjects recruited in the study monitoring phase to each of two levels of intervention; (5) Conduct a process-and-outcome evaluation to assess the efficacy of the two levels of the intervention using NIDA instrumentation; (6) Target rural and Appalachian drug abusers who will make up at least 25% (N = 732) of the study monitoring system subjects and 25% (N = 266) of study intervention subjects who, based on preliminary/pilot studies, are at high risk for HIV and examine risks and possible differences, including migration; and (7) Cooperate with NIDA for standard data collection, evaluation, analyses and publications.

Agency
National Institute of Health (NIH)
Institute
National Institute on Drug Abuse (NIDA)
Type
Research Project--Cooperative Agreements (U01)
Project #
5U01DA008154-03
Application #
2120625
Study Section
Sociobehavioral Subcommittee (DAAR)
Project Start
1993-06-01
Project End
1998-04-30
Budget Start
1995-06-01
Budget End
1996-04-30
Support Year
3
Fiscal Year
1995
Total Cost
Indirect Cost
Name
University of Kentucky
Department
Psychiatry
Type
Schools of Medicine
DUNS #
832127323
City
Lexington
State
KY
Country
United States
Zip Code
40506
Feist-Price, Sonja; Logan, T K; Leukefeld, Carl et al. (2003) Targeting HIV prevention on African American crack and injection drug users. Subst Use Misuse 38:1259-84
Schoeneberger, M L; Logan, T K; Leukefeld, C G (2001) Age differences in HIV risk behaviors and drug treatment utilization among drug users in Kentucky. Subst Use Misuse 36:867-925
Staton, M; Leukefeld, C; Logan, T K (2001) Health service utilization and victimization among incarcerated female substance users. Subst Use Misuse 36:701-16
Warner, B D; Leukefeld, C G (2001) Assessing the differential impact of an hiv prevention intervention: who's putting the message into practice? AIDS Educ Prev 13:479-94
Logan, T K; Leukefeld, C (2000) HIV risk behavior among bisexual and heterosexual drug users. J Psychoactive Drugs 32:239-48
Logan, T K; Leukefeld, C (2000) Sexual and drug use behaviors among female crack users: a multi-site sample. Drug Alcohol Depend 58:237-45
Farabee, D; Leukefeld, C G (1999) Opportunities for AIDS prevention in a rural state in criminal justice and drug treatment settings. Subst Use Misuse 34:617-31
Cottler, L B; Leukefeld, C; Hoffman, J et al. (1998) Effectiveness of HIV risk reduction initiatives among out-of-treatment non-injection drug users. J Psychoactive Drugs 30:279-90
Wechsberg, W M; Desmond, D; Inciardi, J A et al. (1998) HIV prevention protocols: adaptation to evolving trends in drug use. J Psychoactive Drugs 30:291-8
Logan, T K; Leukefeld, C; Farabee, D (1998) Sexual and drug use behaviors among women crack users: implications for prevention. AIDS Educ Prev 10:327-40