In this application, we propose to establish a clinical center to participate as one of 15 centers in the """"""""Mortality and Morbidity in Hemodialysis Patients (MMHD): Full Scale Trial"""""""". This trial has been developed to help identify possible treatment interventions leading to a reduced rate of morbidity and mortality of patients on hemodialysis. Patients will be randomized in a two-by-two factorial clinical trial to determine whether increased delivered hemodialysis and high flux dialysis will reduce morbidity and mortality rates for this patient population.
| Unruh, Mark L; Newman, Anne B; Larive, Brett et al. (2008) The influence of age on changes in health-related quality of life over three years in a cohort undergoing hemodialysis. J Am Geriatr Soc 56:1608-17 |
| Unruh, Mark; Miskulin, Dana; Yan, Guofen et al. (2004) Racial differences in health-related quality of life among hemodialysis patients. Kidney Int 65:1482-91 |
| Unruh, Mark; Yan, Guofen; Radeva, Milena et al. (2003) Bias in assessment of health-related quality of life in a hemodialysis population: a comparison of self-administered and interviewer-administered surveys in the HEMO study. J Am Soc Nephrol 14:2132-41 |
| Miskulin, D C; Athienites, N V; Yan, G et al. (2001) Comorbidity assessment using the Index of Coexistent Diseases in a multicenter clinical trial. Kidney Int 60:1498-510 |
