Abstract

The Biostatistics and Data Management (BDM) Core will continue to play a pivotal role in the Uganda Russia Boston Alcohol Network for Alcohol Research Collaboration on HIV/AIDS (URBAN ARCH) Consortium as a full collaborator in study design, conduct, data management and statistical analyses. Over the next five years, the BDM Core will collaborate closely with URBAN ARCH investigators on studies examining the consequences of alcohol use on comorbidities among people living with HIV so as to increase availability of treatments and improve outcomes. The objectives of the Core are to provide statistical and data management leadership in all phases of research including study design, formulation of hypotheses and outcome measures, data collection, data management, statistical analyses, interpretation of results, and the preparation of publications. The BDM Core brings together an experienced team of investigators with extensive knowledge in underlying scientific and clinical issues in alcohol and HIV/AIDS research. The overarching aims of the BDM Core are to maintain high standards for data quality and statistical analyses. Having this dedicated BDM Core will enhance the synergy and productivity of the Consortium investigators, promote the validity and generalizability of the URBAN ARCH Consortium scientific findings and ultimately elevate the scientific understanding of the relationship between HIV, alcohol consumption, and comorbid health conditions.

Public Health Relevance

The Biostatistics and Data Management Core will collaborate extensively with URBAN ARCH Consortium investigators in all phases of research, from study inception to the publication of research findings. These activities will contribute to the efforts of each study to examine relationships between HIV, alcohol consumption, and comorbid health conditions by increasing the synergy and productivity of Consortium investigators and ultimately ensuring the scientific integrity of results generated from the URBAN ARCH Consortium.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Type
Resource-Related Research Projects--Cooperative Agreements (U24)
Project #
2U24AA020779-06
Application #
9205284
Study Section
Special Emphasis Panel (ZAA1-DD (10)V)
Program Officer
Wang, Joe
Project Start
2011-09-15
Project End
2021-08-31
Budget Start
2016-09-01
Budget End
2017-08-31
Support Year
6
Fiscal Year
2016
Total Cost
$328,964
Indirect Cost
$128,986

  Institution

Name
Boston University
Department
Biostatistics & Other Math Sci
Type
Schools of Public Health
DUNS #
604483045
City
Boston
State
MA
Country
United States
Zip Code
02118

  Publications

Lorkiewicz, Sara A; Ventura, Alicia S; Heeren, Timothy C et al. (2018) Lifetime marijuana and alcohol use, and cognitive dysfunction in people with human immunodeficiency virus infection. Subst Abus 39:116-123
Kim, Theresa W; Walley, Alexander Y; Ventura, Alicia S et al. (2018) Polypharmacy and risk of falls and fractures for patients with HIV infection and substance dependence. AIDS Care 30:150-159
Forman, Leah S; Patts, Gregory J; Coleman, Sharon M et al. (2018) Use of an android phone application for automated text messages in international settings: A case study in an HIV clinical trial in St. Petersburg, Russia. Clin Trials 15:36-43
Wagman, Jennifer A; Samet, Jeffrey H; Cheng, Debbie M et al. (2018) Female Gender and HIV Transmission Risk Behaviors Among People Living with HIV Who Have Ever Used Injection Drugs in St. Petersburg, Russia. AIDS Behav 22:2830-2839
Adong, Julian; Lindan, Christina; Fatch, Robin et al. (2018) The Relationship Between Spirituality/Religiousness and Unhealthy Alcohol Use Among HIV-Infected Adults in Southwestern Uganda. AIDS Behav 22:1802-1813
Coleman, Sharon M; Gnatienko, Natalia; Lloyd-Travaglini, Christine A et al. (2018) False-positive HIV diagnoses: lessons from Ugandan and Russian research cohorts. HIV Clin Trials 19:15-22
Gnatienko, Natalia; Freiberg, Matthew S; Blokhina, Elena et al. (2018) Design of a randomized controlled trial of zinc supplementation to improve markers of mortality and HIV disease progression in HIV-positive drinkers in St. Petersburg, Russia. HIV Clin Trials 19:101-111
Saitz, Richard; Mesic, Aldina; Ventura, Alicia S et al. (2018) Alcohol Consumption and Bone Mineral Density in People with HIV and Substance Use Disorder: A Prospective Cohort Study. Alcohol Clin Exp Res :
Hahn, Judith A; Cheng, Debbie M; Emenyonu, Nneka I et al. (2018) Alcohol Use and HIV Disease Progression in an Antiretroviral Naive Cohort. J Acquir Immune Defic Syndr 77:492-501
Idrisov, Bulat; Lunze, Karsten; Cheng, Debbie M et al. (2017) Role of substance use in HIV care cascade outcomes among people who inject drugs in Russia. Addict Sci Clin Pract 12:30

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