The Administrative Core serves critical leadership and identity roles for the NEALE. The Administrative Core was designed to keep a high level of regulation over the handling, processing, and analysis of laboratory samples and resulting data thereby freeing the laboratory scientists to focus on the scientific aspects of the project. Dr. Miller will serve as Center Director and as lead of the Administrative core will oversee the Center Administrator. Dr. Waller will oversee the Quality Control Officer and Dr. Clifford will oversee the Database Engineer. Together, these three investigators will bring a high degree of organization and management experience to the NEALE. The overall goals of the NEALE Administrative Core are to provide oversight, to communicate among the NEALE and CHEAR components, and to facilitate the movement of samples and data through the network. These goals will be achieved by pursuing the below objectives: Objective 1. To provide leadership and guidance for the entire NEALE Laboratory Hub. Objective 2. To develop and maintain an infrastructure for the handling of biological samples. Under the NEALE we will use a uniform tracking system for biological samples so that they can be seamlessly followed throughout the process regardless of which assays are being performed. Objective 3. To develop and maintain an infrastructure for the acquisition, storage, and analysis of data. While the CHEAR Data Repository has ultimate authority of CHEAR data, it will be necessary to appropriately collect, collate, and tag the data collected in NEALE. By maintaining a high degree of data integrity during the generation phase we will be able to deliver high quality data to the Data Repository. Objective 4. To facilitate communication between the CHEAR Coordinating Center and the NEALE, as well as among the other CHEAR components. The Administrative Core is composed of a diverse group of individual with an expansive breadth of experience in administration, laboratory science, data science, and informatics. This core is poised to lead the NEALE in this new research platform and contribute to the overall mission of the CHEAR program.

Agency
National Institute of Health (NIH)
Institute
National Institute of Environmental Health Sciences (NIEHS)
Type
Resource-Related Research Multi-Component Projects and Centers Cooperative Agreements (U2C)
Project #
1U2CES026560-01
Application #
9062179
Study Section
Special Emphasis Panel (ZES1-LWJ-J (UC))
Project Start
2015-09-30
Project End
2019-08-31
Budget Start
2015-09-01
Budget End
2016-08-31
Support Year
1
Fiscal Year
2015
Total Cost
$577,707
Indirect Cost
$195,468
Name
Emory University
Department
Type
DUNS #
066469933
City
Atlanta
State
GA
Country
United States
Zip Code
30322
Wright, Robert O; Teitelbaum, Susan; Thompson, Claudia et al. (2018) The child health exposure analysis resource as a vehicle to measure environment in the environmental influences on child health outcomes program. Curr Opin Pediatr 30:285-291
Smirnov, Aleksandr; Jia, Wei; Walker, Douglas I et al. (2018) ADAP-GC 3.2: Graphical Software Tool for Efficient Spectral Deconvolution of Gas Chromatography-High-Resolution Mass Spectrometry Metabolomics Data. J Proteome Res 17:470-478
Chandler, Joshua D; Horati, Hamed; Walker, Douglas I et al. (2018) Determination of thiocyanate in exhaled breath condensate. Free Radic Biol Med 126:334-340
Frediani, Jennifer K; Naioti, Eric A; Vos, Miriam B et al. (2018) Arsenic exposure and risk of nonalcoholic fatty liver disease (NAFLD) among U.S. adolescents and adults: an association modified by race/ethnicity, NHANES 2005-2014. Environ Health 17:6
Hu, Xin; Chandler, Joshua D; Park, Soojin et al. (2018) Low-dose cadmium disrupts mitochondrial citric acid cycle and lipid metabolism in mouse lung. Free Radic Biol Med 131:209-217
Niedzwiecki, Megan M; Samant, Pradnya; Walker, Douglas I et al. (2018) Human Suction Blister Fluid Composition Determined Using High-Resolution Metabolomics. Anal Chem 90:3786-3792
Wolff, Mary S; Buckley, Jessie P; Engel, Stephanie M et al. (2017) Emerging exposures of developmental toxicants. Curr Opin Pediatr 29:218-224
Johnson, Caroline H; Athersuch, Toby J; Collman, Gwen W et al. (2017) Yale school of public health symposium on lifetime exposures and human health: the exposome; summary and future reflections. Hum Genomics 11:32
Uppal, Karan; Walker, Douglas I; Liu, Ken et al. (2016) Computational Metabolomics: A Framework for the Million Metabolome. Chem Res Toxicol 29:1956-1975
Jones, Dean P (2016) Hydrogen peroxide and central redox theory for aerobic life: A tribute to Helmut Sies: Scout, trailblazer, and redox pioneer. Arch Biochem Biophys 595:13-8

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