Virginia Commonwealth University (VCU) seeks funding for an Institutional Clinical and Translational Science Award (CTSA). This opportunity comes at a pivotal phase in VCU's growth and development as a premier biomedical research institution and coincides with significant institutional commitment and direction recommended by the Board of Visitors. To accomplish the goals ofthe CTSA initiative, VCU has established a comprehensive matrix center, the Center for Clinical and Translational Research (CCTR). The CCTR will facilitate the development of new partnerships and new initiatives that will extend our research base of fed- eral, private, and industry sponsored awards. Our already strong research program will be encouraged and abetted by a cultural transformation to support translational science and an influx of newly recruited multi- disciplinary investigators. The CCTR leverages substantial existing resources to encourage and support novel research methodologies at VCU. Emphasis is placed on three areas of research strength;namely substance abuse, women's health and rehabilitation science. Pilot funds will be awarded to support innova- tion and community engagement research in these areas. Architecture for a Clinical and Translational Data Environment, an enterprise data warehouse, and a collaborative web portal to facilitate data sharing across VCU, VCU Health System (VCUHS), other CTSA sites and national research networks has been developed A Research Incubator provides biostatistical support, facilitates research, encourages research in research ethics and provides guidance in regulatory issues. Strategies to enhance research subject participation, facilities for the conduction of human research, and access to the Mid-Atlantic Twin Registry are described. Centralized management of and access to a rich array of research resources will be accomplished through the CCTR. Our students will enroll in trans-disciplinary educational cumcula which encourage team building including both a MS and a PhD in Clinical and Translational Science. CCTR will strengthen ties with our affiliates and community partners to make better use of their unique resources and respond to their needs.

Public Health Relevance

Effective delivery of research which moves from the bench to the bedside to the community requires a transformation of research practice at every level. The present grant will support the efforts of VCU to strengthen ties with our affiliates and community partners to make better use of their unique resources and respond to their needs.

Agency
National Institute of Health (NIH)
Institute
National Center for Advancing Translational Sciences (NCATS)
Type
Linked Specialized Center Cooperative Agreement (UL1)
Project #
5UL1TR000058-05
Application #
8643313
Study Section
Special Emphasis Panel (ZRR1)
Program Officer
Sufian, Meryl
Project Start
2010-07-01
Project End
2015-03-31
Budget Start
2014-04-01
Budget End
2015-03-31
Support Year
5
Fiscal Year
2014
Total Cost
Indirect Cost
Name
Virginia Commonwealth University
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
City
Richmond
State
VA
Country
United States
Zip Code
23298
Ajmera, Veeral; Belt, Patricia; Wilson, Laura A et al. (2018) Among Patients With Nonalcoholic Fatty Liver Disease, Modest Alcohol Use Is Associated With Less Improvement in Histologic Steatosis and Steatohepatitis. Clin Gastroenterol Hepatol 16:1511-1520.e5
Carbone, Salvatore; Canada, Justin M; Billingsley, Hayley E et al. (2018) Effects of empagliflozin on cardiorespiratory fitness and significant interaction of loop diuretics. Diabetes Obes Metab 20:2014-2018
Kaspar, Cristin D W; Sanderson, Keia; Ozen, Seza et al. (2018) Pediatric Nephrology and Rheumatology Practice Patterns in Granulomatosis with Polyangiitis: A Midwest Pediatric Nephrology Consortium Study. Int J Nephrol 2018:8413096
Savage, Jeanne E; Rose, Richard J; Pulkkinen, Lea et al. (2018) Early maturation and substance use across adolescence and young adulthood: A longitudinal study of Finnish twins. Dev Psychopathol 30:79-92
Buckley, Leo F; Canada, Justin M; Del Buono, Marco G et al. (2018) Low NT-proBNP levels in overweight and obese patients do not rule out a diagnosis of heart failure with preserved ejection fraction. ESC Heart Fail 5:372-378
Eastman, Meridith L; Verhulst, Brad; Rappaport, Lance M et al. (2018) Age-Related Differences in the Structure of Genetic and Environmental Contributions to Types of Peer Victimization. Behav Genet 48:421-431
Calderwood, Charles; Ackerman, Phillip L (2018) Modeling intraindividual variation in unsafe driving in a naturalistic commuting environment. J Occup Health Psychol :
Bean, M K; Ingersoll, K S; Powell, P et al. (2018) Impact of motivational interviewing on outcomes of an adolescent obesity treatment: results from the MI Values randomized controlled pilot trial. Clin Obes 8:323-326
Bean, Melanie K; Brady Spalding, Bethany; Theriault, Elizabeth et al. (2018) Salad Bars Increased Selection and Decreased Consumption of Fruits and Vegetables 1 Month After Installation in Title I Elementary Schools: A Plate Waste Study. J Nutr Educ Behav 50:589-597
Means, Kimberly N; Gentry, Amanda E; Nguyen, Tammy T (2018) Intravenous Continuous Infusion vs. Oral Immediate-release Diltiazem for Acute Heart Rate Control. West J Emerg Med 19:417-422

Showing the most recent 10 out of 380 publications