In just over four years, the Weill Cornell Medical Center Clinical and Translational Science Center (CTSC) has established a strong and highly effective clinical and translational science infrastructure spanning six diverse partners, each a center of excellence: Memorial Sloan-Kettering Cancer Center; Hospital for Special Surgery; Hunter College School of Nursing. Hunter College Gene Center-a Research Center for Minority Institutions (RCMI); Cornell University Cooperative Extension; and Cornell University, Ithaca. The mission of the CTSC in continuation is to leverage the resources and expertise of this rich multi-institutional partnership to create new interdisciplinary teams and support cutting-edge research from bench to bedside to community to health care practice. The proposed grant adds a new partner, the Animal Medical Center a few blocks from WCMC, to increase collaboration with Cornell University College of Veterinary Medicine. Jointly, they bring a new dimension to our CTSC research and their expertise in small animals will enhance pre-clinical research in the area of drug discovery and device development. Built on the accomplishments achieved during the initial funding period, the strategic plans for the next five years are geared to rapidly advance translational science discoveries by: 1) Enhancing the Drug Discovery Pipeline; 2) Increasing the Breadth of Research Resources; 3) Adding New Expertise and Training Programs; and 4) Enhancing Community Engagement and Dissemination. Moving forward, the anticipated benefits of fostering Innovation through Collaboration during the next funding period include: 1) Further generation of novel ideas leading to drug development and medical devices which benefit patient care; 2) Increased collaborative efforts with partners and industry, to facilitate research to improve the general health ofthe public; 3) Enhanced clinical translational (C/T) educational programs in comparative effectiveness research, global health and health information technology; 4) Enhanced community engagement; 5) Increased centralization of C/T research, education, infrastructure, and databases; and 6) Enhanced evaluation and tracking of CTSC programs.

Public Health Relevance

The broad research support infrastructure ofthe CTSC and its programs to foster interactions among basic scientists, clinicians and community practitioners are key to the rapid translation of basic science discoveries into effective clinical practice. Our CTSC is distinct in the heterogeneity of its component institutions, providing unparalleled opportunities for collaboration and training in all areas of biomedical sciences. PROJECT/RERFORMANCE SITE(S) (if additional space is needed, use

Agency
National Institute of Health (NIH)
Institute
National Center for Advancing Translational Sciences (NCATS)
Type
Linked Specialized Center Cooperative Agreement (UL1)
Project #
3UL1TR000457-09S1
Application #
9131841
Study Section
Special Emphasis Panel (ZRR1-CR-1 (01))
Program Officer
Sufian, Meryl
Project Start
2007-09-17
Project End
2017-05-31
Budget Start
2015-09-05
Budget End
2016-05-31
Support Year
9
Fiscal Year
2015
Total Cost
$42,255
Indirect Cost
$17,326
Name
Weill Medical College of Cornell University
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
060217502
City
New York
State
NY
Country
United States
Zip Code
10065
Chiang, G C; Hu, J; Morris, E et al. (2018) Quantitative Susceptibility Mapping of the Thalamus: Relationships with Thalamic Volume, Total Gray Matter Volume, and T2 Lesion Burden. AJNR Am J Neuroradiol :
Chen, Cindy; Wulff, Regina T; Sholle, Evan T et al. (2018) Evaluating Generalizability of a Biospecimen Informatics Approach: Support for Local Requirements and Best Practices. AMIA Jt Summits Transl Sci Proc 2017:55-62
Mann, Justin M; Wu, Xian; Christos, Paul et al. (2018) The State of Surgical Axillary Management and Adjuvant Radiotherapy for Early-stage Invasive Breast Cancer in the Modern Era. Clin Breast Cancer 18:e477-e493
Bonnevie, Edward D; Delco, Michelle L; Bartell, Lena R et al. (2018) Microscale frictional strains determine chondrocyte fate in loaded cartilage. J Biomech 74:72-78
Roboz, Gail J; Ritchie, Ellen K; Dault, Yulia et al. (2018) Phase I trial of plerixafor combined with decitabine in newly diagnosed older patients with acute myeloid leukemia. Haematologica 103:1308-1316
Batavia, Ashita S; Severe, Patrice; Lee, Myung Hee et al. (2018) Blood pressure and mortality in a prospective cohort of HIV-infected adults in Port-au-Prince, Haiti. J Hypertens 36:1533-1539
Mody, Kalgi; Kaur, Savneet; Mauer, Elizabeth A et al. (2018) Benzodiazepines and Development of Delirium in Critically Ill Children: Estimating the Causal Effect. Crit Care Med 46:1486-1491
Cruz, Nicole M; Sugita, Mayumi; Ewing-Crystal, Nathan et al. (2018) Selection and characterization of antibody clones are critical for accurate flow cytometry-based monitoring of CD123 in acute myeloid leukemia. Leuk Lymphoma 59:978-982
Phongtankuel, Veerawat; Adelman, Ronald D; Trevino, Kelly et al. (2018) Association Between Nursing Visits and Hospital-Related Disenrollment in the Home Hospice Population. Am J Hosp Palliat Care 35:316-323
Delco, Michelle L; Bonnevie, Edward D; Bonassar, Lawrence J et al. (2018) Mitochondrial dysfunction is an acute response of articular chondrocytes to mechanical injury. J Orthop Res 36:739-750

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