In just over four years, the Weill Cornell Medical Center Clinical and Translational Science Center (CTSC) has established a strong and highly effective clinical and translational science infrastructure spanning six diverse partners, each a center of excellence: Memorial Sloan-Kettering Cancer Center; Hospital for Special Surgery; Hunter College School of Nursing. Hunter College Gene Center-a Research Center for Minority Institutions (RCMI); Cornell University Cooperative Extension; and Cornell University, Ithaca. The mission of the CTSC in continuation is to leverage the resources and expertise of this rich multi-institutional partnership to create new interdisciplinary teams and support cutting-edge research from bench to bedside to community to health care practice. The proposed grant adds a new partner, the Animal Medical Center a few blocks from WCMC, to increase collaboration with Cornell University College of Veterinary Medicine. Jointly, they bring a new dimension to our CTSC research and their expertise in small animals will enhance pre-clinical research in the area of drug discovery and device development. Built on the accomplishments achieved during the initial funding period, the strategic plans for the next five years are geared to rapidly advance translational science discoveries by: 1) Enhancing the Drug Discovery Pipeline; 2) Increasing the Breadth of Research Resources; 3) Adding New Expertise and Training Programs; and 4) Enhancing Community Engagement and Dissemination. Moving forward, the anticipated benefits of fostering Innovation through Collaboration during the next funding period include: 1) Further generation of novel ideas leading to drug development and medical devices which benefit patient care; 2) Increased collaborative efforts with partners and industry, to facilitate research to improve the general health ofthe public; 3) Enhanced clinical translational (C/T) educational programs in comparative effectiveness research, global health and health information technology; 4) Enhanced community engagement; 5) Increased centralization of C/T research, education, infrastructure, and databases; and 6) Enhanced evaluation and tracking of CTSC programs.

Public Health Relevance

The broad research support infrastructure ofthe CTSC and its programs to foster interactions among basic scientists, clinicians and community practitioners are key to the rapid translation of basic science discoveries into effective clinical practice. Our CTSC is distinct in the heterogeneity of its component institutions, providing unparalleled opportunities for collaboration and training in all areas of biomedical sciences. PROJECT/RERFORMANCE SITE(S) (if additional space is needed, use

Agency
National Institute of Health (NIH)
Institute
National Center for Advancing Translational Sciences (NCATS)
Type
Linked Specialized Center Cooperative Agreement (UL1)
Project #
4UL1TR000457-10
Application #
9100527
Study Section
Special Emphasis Panel (ZRR1)
Program Officer
Sufian, Meryl
Project Start
2007-09-17
Project End
2017-05-31
Budget Start
2016-06-01
Budget End
2017-05-31
Support Year
10
Fiscal Year
2016
Total Cost
Indirect Cost
Name
Weill Medical College of Cornell University
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
060217502
City
New York
State
NY
Country
United States
Zip Code
10065
Harrington, John S; Schenck, Edward J; Oromendia, Clara et al. (2018) Acute respiratory distress syndrome without identifiable risk factors: A secondary analysis of the ARDS network trials. J Crit Care 47:49-54
Pianko, Matthew J; Funt, Samuel A; Page, David B et al. (2018) Efficacy and toxicity of therapy immediately after treatment with nivolumab in relapsed multiple myeloma. Leuk Lymphoma 59:221-224
Francis, Jenny K R; de Roche, Ariel M; Mauro, Christine et al. (2018) Adolescent-Parent Dyadic Retention in an Interview Study and Changes in Willingness to Participate in a Hypothetical Microbicide Safety Study. J Pediatr Adolesc Gynecol 31:592-596
Allen, Baxter B; Forgacs, Peter B; Fakhar, Malik A et al. (2018) Association of Seizure Occurrence with Aneurysm Treatment Modality in Aneurysmal Subarachnoid Hemorrhage Patients. Neurocrit Care 29:62-68
Boulad, Farid; Shore, Tsiporah; van Besien, Koen et al. (2018) Safety and efficacy of plerixafor dose escalation for the mobilization of CD34+ hematopoietic progenitor cells in patients with sickle cell disease: interim results. Haematologica 103:770-777
Hausman-Kedem, Moran; Kosofsky, Barry E; Ross, Gail et al. (2018) Accuracy of Reported Community Diagnosis of Autism Spectrum Disorder. J Psychopathol Behav Assess 40:367-375
Geyer, Mark B; Manjunath, Shwetha H; Evans, Andrew G et al. (2018) Concurrent therapy of chronic lymphocytic leukemia and Philadelphia chromosome-positive acute lymphoblastic leukemia utilizing CD19-targeted CAR T-cells. Leuk Lymphoma 59:1717-1721
Curley, William H; Forgacs, Peter B; Voss, Henning U et al. (2018) Characterization of EEG signals revealing covert cognition in the injured brain. Brain 141:1404-1421
Pak, Linda M; Chakraborty, Jayasree; Gonen, Mithat et al. (2018) Quantitative Imaging Features and Postoperative Hepatic Insufficiency: A Multi-Institutional Expanded Cohort. J Am Coll Surg 226:835-843
Staudt, Michelle R; Salit, Jacqueline; Kaner, Robert J et al. (2018) Altered lung biology of healthy never smokers following acute inhalation of E-cigarettes. Respir Res 19:78

Showing the most recent 10 out of 756 publications