The Ohio State University created the Center for Clinical and Translational Science (CCTS) to catalyze research teams and facilitate innovation through creation of an environment that fosters translation of knowledge to improve human health. The Center will accomplish four specific aims: 1) Build on the unique and diverse strengths of our institution to create an integrated academic home for innovative, team-oriented clinical and translational science;2) Enhance and nurture the career development of highly trained investigators, with an emphasis on innovation and transdisciplinary science;3) Integrate and enhance an administrative infrastructure to optimize the efficient conduct of the highest quality, generalizable clinical and translational science that is relevant to the community setting;4) Develop, enhance and integrate a portfolio of outstanding shared resources in support of transformative clinical and translational research. The CCTS will continue to focus on integrating the traditional biomedical research process (basic scientific discovery with translation to the bedside to dissemination into the community for improved patient outcomes) with a public health model (surveillance to prevention to response). By incorporating this bi-directional model in the creation of a robust translational science infrastructure, the OSU CCTS will foster both the traditional """"""""discovery to best practice"""""""" paradigm as well as taking advantage of the insight garnered from our foundation of excellence in clinical care to stimulate basic discovery and clinical research inquiry. The vision and specific aims will be achieved through an integrated model of governance and partnership, home, and leadership for clinical and translational research spanning NCH and OSU;focused pilot funding initiatives for new team development within an innovation ecosystem;unique educational and training architecture which integrates acquisition of core competencies in research methodology, interpretation of results, implementation of findings, design thinking, team leadership skills and business acumen with rigorous discipline-specific laboratory (bench, clinical or community) training;and a clinical and translational science infrastructure that is cohesive, innovative and adaptable and more effective than the services that currently exist in order to ensure provision of the full range of disease-agnostic scientific resources needed to traverse the continuum of research from T1-4.
(See Instructions): The Center for Clinical and Translational Science will improve human health by bringing the benefits of science more quickly into patient care.
|Keenan, Brendan T; Kim, Jinyoung; Singh, Bhajan et al. (2018) Recognizable clinical subtypes of obstructive sleep apnea across international sleep centers: a cluster analysis. Sleep 41:|
|Pisoni, David B; Broadstock, Arthur; Wucinich, Taylor et al. (2018) Verbal Learning and Memory After Cochlear Implantation in Postlingually Deaf Adults: Some New Findings with the CVLT-II. Ear Hear 39:720-745|
|Barrie, Elizabeth S; Pinsonneault, Julia K; Sadee, Wolfgang et al. (2018) Testing genetic modifiers of behavior and response to atomoxetine in autism spectrum disorder with ADHD. J Dev Phys Disabil 30:355-371|
|Garcia-Mauriño, Cristina; Moore-Clingenpeel, Melissa; Wallihan, Rebecca et al. (2018) Discharge Criteria for Bronchiolitis: An Unmet Need. Pediatr Infect Dis J 37:514-519|
|Amici, Stephanie A; Young, Nicholas A; Narvaez-Miranda, Janiret et al. (2018) CD38 Is Robustly Induced in Human Macrophages and Monocytes in Inflammatory Conditions. Front Immunol 9:1593|
|Brown, Angela M; Opoku, Faustina Ottie; Stenger, Michael R (2018) Neonatal Contrast Sensitivity and Visual Acuity: Basic Psychophysics. Transl Vis Sci Technol 7:18|
|Christian, Lisa M; Kowalsky, Jennifer M; Mitchell, Amanda M et al. (2018) Associations of postpartum sleep, stress, and depressive symptoms with LPS-stimulated cytokine production among African American and White women. J Neuroimmunol 316:98-106|
|Awad, Hamdy; Bratasz, Anna; Nuovo, Gerard et al. (2018) MiR-155 deletion reduces ischemia-induced paralysis in an aortic aneurysm repair mouse model: Utility of immunohistochemistry and histopathology in understanding etiology of spinal cord paralysis. Ann Diagn Pathol 36:12-20|
|Moberly, Aaron C; Patel, Tirth R; Castellanos, Irina (2018) Relations Between Self-reported Executive Functioning and Speech Perception Skills in Adult Cochlear Implant Users. Otol Neurotol 39:250-257|
|Emery, Charles F; Stoney, Catherine M; Thayer, Julian F et al. (2018) Sex and family history of cardiovascular disease influence heart rate variability during stress among healthy adults. J Psychosom Res 110:54-60|
Showing the most recent 10 out of 473 publications