This is a new project which the lab has just started to work on. In collaboration with James Meschia (Mayo Clinic) we will be carrying out an affected sibpair study ischaemic stroke. Currently, the project is at the sample collection phase. The first genotyping will occur in 2003

Agency
National Institute of Health (NIH)
Institute
National Institute on Aging (NIA)
Type
Intramural Research (Z01)
Project #
1Z01AG000954-01
Application #
6668182
Study Section
(LNG)
Project Start
Project End
Budget Start
Budget End
Support Year
1
Fiscal Year
2002
Total Cost
Indirect Cost
Name
Aging
Department
Type
DUNS #
City
State
Country
United States
Zip Code
Cheng, Yu-Ching; Stanne, Tara M; Giese, Anne-Katrin et al. (2016) Genome-Wide Association Analysis of Young-Onset Stroke Identifies a Locus on Chromosome 10q25 Near HABP2. Stroke 47:307-16
Bluher, A; Devan, W J; Holliday, E G et al. (2015) Heritability of young- and old-onset ischaemic stroke. Eur J Neurol 22:1488-91
Carty, Cara L; Keene, Keith L; Cheng, Yu-Ching et al. (2015) Meta-Analysis of Genome-Wide Association Studies Identifies Genetic Risk Factors for Stroke in African Americans. Stroke 46:2063-8
Auer, Paul L; Nalls, Mike; Meschia, James F et al. (2015) Rare and Coding Region Genetic Variants Associated With Risk of Ischemic Stroke: The NHLBI Exome Sequence Project. JAMA Neurol 72:781-8
Malik, Rainer; Freilinger, Tobias; Winsvold, Bendik S et al. (2015) Shared genetic basis for migraine and ischemic stroke: A genome-wide analysis of common variants. Neurology 84:2132-45
Traylor, Matthew; Mäkelä, Kari-Matti; Kilarski, Laura L et al. (2014) A novel MMP12 locus is associated with large artery atherosclerotic stroke using a genome-wide age-at-onset informed approach. PLoS Genet 10:e1004469
Ay, Hakan; Arsava, Ethem Murat; Andsberg, Gunnar et al. (2014) Pathogenic ischemic stroke phenotypes in the NINDS-stroke genetics network. Stroke 45:3589-96
Malik, Rainer; Bevan, Steve; Nalls, Michael A et al. (2014) Multilocus genetic risk score associates with ischemic stroke in case-control and prospective cohort studies. Stroke 45:394-402
Ibrahim-Verbaas, Carla A; Fornage, Myriam; Bis, Joshua C et al. (2014) Predicting stroke through genetic risk functions: the CHARGE Risk Score Project. Stroke 45:403-12
Kim, Daniel Seung; Crosslin, David R; Auer, Paul L et al. (2014) Rare coding variation in paraoxonase-1 is associated with ischemic stroke in the NHLBI Exome Sequencing Project. J Lipid Res 55:1173-8

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