We are currently discussing possible new vaccine candidates for therapy of herpes simplex, and planning new clinical trials.Among these is a live, replication-defective HSV-2 vaccine that we showed this past year to be effective in the immunotherapy of genital herpes in the gunea pig model.

Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Intramural Research (Z01)
Project #
1Z01AI000836-08
Application #
7196647
Study Section
(LCID)
Project Start
Project End
Budget Start
Budget End
Support Year
8
Fiscal Year
2005
Total Cost
Indirect Cost
Name
Niaid Extramural Activities
Department
Type
DUNS #
City
State
Country
United States
Zip Code
Marques, A R; Straus, S E; Fahle, G et al. (2001) Lack of association between HSV-1 DNA in the brain, Alzheimer's disease and apolipoprotein E4. J Neurovirol 7:82-3
Marques, A R; Straus, S E (2000) Herpes simplex type 2 infections--an update. Adv Intern Med 45:175-208
Marques, A R; Straus, S E (2000) Herpes simplex type 2 infections--an update. Dis Mon 46:325-59