Protein tyrosine phosphatase (PTP) may play a key role in controlling cell growth and proliferation as well as possibly in tumor suppression. Two different cDNAs encoding PTP have been isolated from mouse testis and T-Cell cDNA libraries, and their nucleotide sequence determined. The amino acid sequences of these two PTP were also deduced and their potential antigenic peptides are being chemically synthesized in order to obtain specific antibodies.

Agency
National Institute of Health (NIH)
Institute
National Institute of Environmental Health Sciences (NIEHS)
Type
Intramural Research (Z01)
Project #
1Z01ES061046-01
Application #
3855942
Study Section
Project Start
Project End
Budget Start
Budget End
Support Year
1
Fiscal Year
1991
Total Cost
Indirect Cost
City
State
Country
United States
Zip Code