We are attempting to understand the intracellular pathways which regulate the growth and migration of vascular smooth muscle cells (smc). This is of particular interest since smooth muscle cell proliferation and migration is thought to be largely responsible to restenosis following balloon angioplasty, as well as being an initial event in atherosclerosis. Using techniques of molecular and cell biology, we are attempting to understand how extracellular (outside) signals are converted into pathways inside the cell that stimulate proliferation and movement.

Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Intramural Research (Z01)
Project #
1Z01HL004927-01
Application #
3779627
Study Section
Project Start
Project End
Budget Start
Budget End
Support Year
1
Fiscal Year
1993
Total Cost
Indirect Cost
Name
National Heart, Lung, and Blood Institute
Department
Type
DUNS #
City
State
Country
United States
Zip Code