This is an ongoing project to determine the susceptibility of brown tree snakes (Boiga irregularis) to ophidian paramyxovirus infection and to study the pathogenesis of viral infections with this important group of snake pathogens. Two newly-isolated strains of ophidian paramyxovirus are currently being studied, in addition to further research with a previously isolated virus. Following inoculation with these viruses, brown tree snakes have become clinically ill and up to 50% have died in some inoculation trials. Paramyxoviruses have been isolated from infected snakes and propagated in cell culture and embryonated chicken eggs; the viruses have also been identified via transmission electron microscopy. Snake inoculation trials are continuing at the National Zoo.

Agency
National Institute of Health (NIH)
Institute
National Center for Research Resources (NCRR)
Type
Intramural Research (Z01)
Project #
1Z01RR000095-06
Application #
2583128
Study Section
Virology Study Section (VR)
Project Start
Project End
Budget Start
Budget End
Support Year
6
Fiscal Year
1996
Total Cost
Indirect Cost
Name
National Center for Research Resources
Department
Type
DUNS #
City
State
Country
United States
Zip Code