Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Intramural Research (Z01)
Project #
1Z01SC006538-04
Application #
6163278
Study Section
Special Emphasis Panel (M)
Project Start
Project End
Budget Start
Budget End
Support Year
4
Fiscal Year
1997
Total Cost
Indirect Cost
Name
National Cancer Institute Division of Clinical Sciences
Department
Type
DUNS #
City
State
Country
United States
Zip Code
Ning, Yang-Min; Figg, William D; Dahut, William L (2009) Reversal of docetaxel resistance with bevacizumab and thalidomide. Clin Genitourin Cancer 7:E37-8
Ge, Yun; Byun, Jung S; De Luca, Paola et al. (2008) Combinatorial antileukemic disruption of oxidative homeostasis and mitochondrial stability by the redox reactive thalidomide 2-(2,4-difluoro-phenyl)-4,5,6,7-tetrafluoro-1H-isoindole-1,3(2H)-dione (CPS49) and flavopiridol. Mol Pharmacol 74:872-83
Li, Haiqing; Raia, Valentina; Bertolini, Francesco et al. (2008) Circulating endothelial cells as a therapeutic marker for thalidomide in combined therapy with chemotherapy drugs in a human prostate cancer model. BJU Int 101:884-8
Li, Haiqing; Price, Douglas K; Figg, William D (2007) ADH1, an N-cadherin inhibitor, evaluated in preclinical models of angiogenesis and androgen-independent prostate cancer. Anticancer Drugs 18:563-8
Lakhani, Nehal J; Sparreboom, Alex; Xu, Xia et al. (2007) Characterization of in vitro and in vivo metabolic pathways of the investigational anticancer agent, 2-methoxyestradiol. J Pharm Sci 96:1821-31
Gojo, Ivana; Jiemjit, Anchalee; Trepel, Jane B et al. (2007) Phase 1 and pharmacologic study of MS-275, a histone deacetylase inhibitor, in adults with refractory and relapsed acute leukemias. Blood 109:2781-90
Ge, Yun; Montano, Idalia; Rustici, Gabriella et al. (2006) Selective leukemic-cell killing by a novel functional class of thalidomide analogs. Blood 108:4126-35
Warfel, Noel A; Lepper, Erin R; Zhang, Chunyu et al. (2006) Importance of the stress kinase p38alpha in mediating the direct cytotoxic effects of the thalidomide analogue, CPS49, in cancer cells and endothelial cells. Clin Cancer Res 12:3502-9
Lepper, Erin R; Smith, Nicola F; Cox, Michael C et al. (2006) Thalidomide metabolism and hydrolysis: mechanisms and implications. Curr Drug Metab 7:677-85
Sion, Amy M; Figg, William D (2006) Lysyl oxidase (LOX) and hypoxia-induced metastases. Cancer Biol Ther 5:909-11

Showing the most recent 10 out of 47 publications