The Section is the statistical and data management component of the Division of Clinical Sciences (DCS). The Section provides statistical leadership and data management consultation for major activities of the Division, and is involved in the design, conduct, monitoring, and statistical analyses of intramural and national multicenter clinical trials of experimental treatments for cancer, and intramural clinical trials for treatment of AIDS. Other major collaborative efforts include studies to identify important prognostic and treatment selection factors, evaluate diagnostic procedures, develop improved staging systems, and assist investigators in the design, execution, and analyses of major in vitro drug testing studies. The Section develops new statistical designs and biometric methods related to the development and evaluation of new cancer and AIDS treatments. The Section maintains computerized data collection systems for intramural and national multicenter clinical protocols, and it works closely with interested branches to improve data recording and retrieval. The Section is working to develop a comprehensive clinical data base for the DCS and maintains a unified system for tracking basic information on all patients registered on DCS treatment protocols. Approximately 15% of the Sections activities are HIV-AIDS related.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Intramural Research (Z01)
Project #
1Z01SC007202-13
Application #
2456838
Study Section
Special Emphasis Panel (BDMS)
Project Start
Project End
Budget Start
Budget End
Support Year
13
Fiscal Year
1996
Total Cost
Indirect Cost
Name
National Cancer Institute Division of Clinical Sciences
Department
Type
DUNS #
City
State
Country
United States
Zip Code
Toubaji, Antoun; Achtar, Moujahed; Provenzano, Maurizio et al. (2008) Pilot study of mutant ras peptide-based vaccine as an adjuvant treatment in pancreatic and colorectal cancers. Cancer Immunol Immunother 57:1413-20
Miao, Ning; Pingpank, James F; Alexander, H Richard et al. (2008) Percutaneous hepatic perfusion in patients with metastatic liver cancer: anesthetic, hemodynamic, and metabolic considerations. Ann Surg Oncol 15:815-23
Hamada, Akinobu; Sissung, Tristan; Price, Douglas K et al. (2008) Effect of SLCO1B3 haplotype on testosterone transport and clinical outcome in caucasian patients with androgen-independent prostatic cancer. Clin Cancer Res 14:3312-8
Sissung, Tristan M; Danesi, Romano; Price, Douglas K et al. (2008) Association of the CYP1B1*3 allele with survival in patients with prostate cancer receiving docetaxel. Mol Cancer Ther 7:19-26
Schrump, David S; Fischette, Maria R; Nguyen, Dao M et al. (2008) Clinical and molecular responses in lung cancer patients receiving Romidepsin. Clin Cancer Res 14:188-98
Gulley, James L; Aragon-Ching, Jeanny B; Steinberg, Seth M et al. (2008) Kinetics of serum androgen normalization and factors associated with testosterone reserve after limited androgen deprivation therapy for nonmetastatic prostate cancer. J Urol 180:1432-7;discussion 1437
Eng-Wong, Jennifer; Orzano-Birgani, Jennifer; Chow, Catherine K et al. (2008) Effect of raloxifene on mammographic density and breast magnetic resonance imaging in premenopausal women at increased risk for breast cancer. Cancer Epidemiol Biomarkers Prev 17:1696-701
Ahmad, Ejaz; Steinberg, Seth M; Goldin, Lynn et al. (2008) Immunophenotypic features distinguishing familial chronic lymphocytic leukemia from sporadic chronic lymphocytic leukemia. Cytometry B Clin Cytom 74:221-6
Portera, Chia C; Walshe, Janice M; Rosing, Douglas R et al. (2008) Cardiac toxicity and efficacy of trastuzumab combined with pertuzumab in patients with [corrected] human epidermal growth factor receptor 2-positive metastatic breast cancer. Clin Cancer Res 14:2710-6
Klapper, Jacob A; Downey, Stephanie G; Smith, Franz O et al. (2008) High-dose interleukin-2 for the treatment of metastatic renal cell carcinoma : a retrospective analysis of response and survival in patients treated in the surgery branch at the National Cancer Institute between 1986 and 2006. Cancer 113:293-301

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