The causes and consequences of decline in muscle biomechanical quality with aging are unknown. Since it has been postulated that a large portion of age-related loss of mobility and disability with aging is linked to loss of muscle strength, identification of such causes is essential in order to develop therapeutic strategies that may effectively preserve physical ability with aging. This project entails a number of studies that scan a wide range of hypotheses concerning the origin of muscle quality and its consequences with aging. This discovery stage will be followed by more in depth studies that focus on the most promising lines of research.

Agency
National Institute of Health (NIH)
Institute
National Institute on Aging (NIA)
Type
Investigator-Initiated Intramural Research Projects (ZIA)
Project #
1ZIAAG000995-05
Application #
10012636
Study Section
Project Start
Project End
Budget Start
Budget End
Support Year
5
Fiscal Year
2019
Total Cost
Indirect Cost
Name
National Institute on Aging
Department
Type
DUNS #
City
State
Country
Zip Code
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