Recurrent non-random genomic alterations are the hallmarks of cancer and the characterization of these imbalances is critical to our understanding of tumorigenesis and cancer progression. We are performing microarray based-comparative genomic hybridization (CGH) on SNP and other oligonucleotide microarrays in neuroblastoma. We have recently began using next generation sequencing techniques to detect all of the structural alterations found in neuroblasotmas including small and large insertions and deletions as well as translocations.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Investigator-Initiated Intramural Research Projects (ZIA)
Project #
1ZIABC010592-08
Application #
8349059
Study Section
Project Start
Project End
Budget Start
Budget End
Support Year
8
Fiscal Year
2011
Total Cost
$87,207
Indirect Cost
Name
National Cancer Institute Division of Basic Sciences
Department
Type
DUNS #
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State
Country
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