NEIBank and EyeBrowse (a dedicated genome browser for eye-expressed genes, produced in collaboration with CIT. http://eyebrowse.cit.nih.gov/genome/)consitiute a resource for eye research worldwide. While computational support has been greatly reduced, databases of expressed sequences, human eye disease genes and databases of candidate eye disease regions of the genome are still maintained at a slower rate.In addition, sequence verified clones and other resources, particularly custom yeast 2-hybrid cDNA libraries for functional genomics are maintained and continue to be distributed to other laboratories and institutions.

Agency
National Institute of Health (NIH)
Institute
National Eye Institute (NEI)
Type
Investigator-Initiated Intramural Research Projects (ZIA)
Project #
1ZIAEY000320-16
Application #
8938303
Study Section
Project Start
Project End
Budget Start
Budget End
Support Year
16
Fiscal Year
2014
Total Cost
Indirect Cost
Name
U.S. National Eye Institute
Department
Type
DUNS #
City
State
Country
Zip Code
Todd, Joshua J; Sagar, Vatsala; Lawal, Tokunbor A et al. (2018) Correlation of phenotype with genotype and protein structure in RYR1-related disorders. J Neurol :
Liu, Yutao; Munro, Drew; Layfield, David et al. (2011) Serial analysis of gene expression (SAGE) in normal human trabecular meshwork. Mol Vis 17:885-93
Bernstein, Steven L; Guo, Yan; Peterson, Katherine et al. (2009) Expressed sequence tag analysis of adult human optic nerve for NEIBank: identification of cell type and tissue markers. BMC Neurosci 10:121
Jaworski, C J; Aryankalayil-John, M; Campos, M M et al. (2009) Expression analysis of human pterygium shows a predominance of conjunctival and limbal markers and genes associated with cell migration. Mol Vis 15:2421-34
Simpanya, Mukoma F; Wistow, Graeme; Gao, James et al. (2008) Expressed sequence tag analysis of guinea pig (Cavia porcellus) eye tissues for NEIBank. Mol Vis 14:2413-27