Abstract

During the past year we have continued enhancement of imaging platforms to guide cardiovascular catheter based treatments. These have included co-registered MRI with conventional X-ray, as well as standalone real-time MRI. We are working closely with industry, through a Collaborative Research and Development Agreement, to introduce motion-corrected roadmaps into clinical practice. We continue to enhance a system for safe patient hemodynamic monitoring and recording during interventional MRI experiments and during transfer between X-ray and MRI. We are applying this work towards adults and children undergoing MRI catheterization, and we are working internally and with industry to enhance this technology. We are developing techniques of MRI that minimize heating of metallic devices, that might allow MRI catheterization using tools previously considered unsafe, or that might enhance the safety of MRI in patients who have implanted devices like pacemakers and defibrillators. We are working closely with industry to transfer our developments into commercial tools that can be used widely in medical care throughout the world.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Investigator-Initiated Intramural Research Projects (ZIA)
Project #
1ZIAHL006039-09
Application #
9787908
Study Section
Project Start
Project End
Budget Start
Budget End
Support Year
9
Fiscal Year
2018
Total Cost
Indirect Cost

  Institution

Name
U.S. National Heart Lung and Blood Inst
Department
Type
DUNS #
City
State
Country
Zip Code

  Publications

Campbell-Washburn, Adrienne E; Rogers, Toby; Stine, Annette M et al. (2018) Right heart catheterization using metallic guidewires and low SAR cardiovascular magnetic resonance fluoroscopy at 1.5 Tesla: first in human experience. J Cardiovasc Magn Reson 20:41
Fischer, Peter; Faranesh, Anthony; Pohl, Thomas et al. (2018) An MR-Based Model for Cardio-Respiratory Motion Compensation of Overlays in X-Ray Fluoroscopy. IEEE Trans Med Imaging 37:47-60
Kakareka, John W; Faranesh, Anthony Z; Pursley, Randall H et al. (2018) Physiological Recording in the MRI Environment (PRiME): MRI-Compatible Hemodynamic Recording System. IEEE J Transl Eng Health Med 6:4100112
Campbell-Washburn, Adrienne E; Tavallaei, Mohammad A; Pop, Mihaela et al. (2017) Real-time MRI guidance of cardiac interventions. J Magn Reson Imaging 46:935-950
Rogers, Toby; Ratnayaka, Kanishka; Khan, Jaffar M et al. (2017) CMR fluoroscopy right heart catheterization for cardiac output and pulmonary vascular resistance: results in 102 patients. J Cardiovasc Magn Reson 19:54
Rogers, Toby; Mahapatra, Srijoy; Kim, Steven et al. (2016) Transcatheter Myocardial Needle Chemoablation During Real-Time Magnetic Resonance Imaging: A New Approach to Ablation Therapy for Rhythm Disorders. Circ Arrhythm Electrophysiol 9:e003926
Rogers, Toby; Ratnayaka, Kanishka; Karmarkar, Parag et al. (2016) Real-time magnetic resonance imaging guidance improves the diagnostic yield of endomyocardial biopsy. JACC Basic Transl Sci 1:376-383
Campbell-Washburn, Adrienne E; Xue, Hui; Lederman, Robert J et al. (2016) Real-time distortion correction of spiral and echo planar images using the gradient system impulse response function. Magn Reson Med 75:2278-85
McGuirt, Delaney; Mazal, Jonathan; Rogers, Toby et al. (2016) X-ray Fused With Magnetic Resonance Imaging to Guide Endomyocardial Biopsy of a Right Ventricular Mass. Radiol Technol 87:622-6
Ratnayaka, Kanishka; Rogers, Toby; Schenke, William H et al. (2016) Magnetic Resonance Imaging-Guided Transcatheter Cavopulmonary Shunt. JACC Cardiovasc Interv 9:959-70

Showing the most recent 10 out of 43 publications