Abstract

We are continuing development of this novel catheter technique. We have collaborated with Dr June-Hong Kim and Dr Renu Virmani to verify the cerclage trajectory in human autopsy heart specimens. We have developed new catheters to simplify the procedure. We are building a manufacturing and prototyping facility for investigational catheter devices. We also are building the preclinical regulatory infrastructure necessary for further development toward Investigational Device Exemption clinical protocols.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Investigator-Initiated Intramural Research Projects (ZIA)
Project #
1ZIAHL006040-01
Application #
8149560
Study Section
Project Start
Project End
Budget Start
Budget End
Support Year
1
Fiscal Year
2010
Total Cost
$201,041
Indirect Cost

  Institution

Name
National Heart, Lung, and Blood Institute
Department
Type
DUNS #
City
State
Country
Zip Code

  Publications

Khan, Jaffar M; Lederman, Robert J; Sanon, Saurabh et al. (2018) Transcatheter Mitral Valve Replacement After Transcatheter Electrosurgical Laceration of Alfieri STItCh (ELASTIC): First-in-Human Report. JACC Cardiovasc Interv 11:808-811
Rogers, Toby; Lederman, Robert J (2018) Percutaneous transaxillary access for TAVR: Another opportunity to stay out of the chest. Catheter Cardiovasc Interv 91:157-158
Kasel, A Markus; Rumpf, Moritz; Frangieh, Antonio H et al. (2018) International LAMPOON: first European experience with laceration of the anterior mitral valve leaflet prior to transseptal transcatheter mitral valve implantation. EuroIntervention 14:746-749
Khan, Jaffar M; Lederman, Robert J (2018) Transcatheter electrosurgery in bipolar or monopolar modes. Catheter Cardiovasc Interv 91:1052-1053
Greenbaum, Adam B; Condado, Jose F; Eng, Marvin et al. (2018) Long or redundant leaflet complicating transcatheter mitral valve replacement: Case vignettes that advocate for removal or reduction of the anterior mitral leaflet. Catheter Cardiovasc Interv 92:627-632
Khan, Jaffar M; Rogers, Toby; Babaliaros, Vasilis C et al. (2018) Predicting Left Ventricular Outflow Tract Obstruction Despite Anterior Mitral Leaflet Resection: The ""Skirt NeoLVOT"". JACC Cardiovasc Imaging 11:1356-1359
Khan, Jaffar M; Dvir, Danny; Greenbaum, Adam B et al. (2018) Transcatheter Laceration of Aortic Leaflets to Prevent Coronary Obstruction During Transcatheter Aortic Valve Replacement: Concept to First-in-Human. JACC Cardiovasc Interv 11:677-689
Khan, Jaffar M; Rogers, Toby; Eng, Marvin H et al. (2018) Guidewire electrosurgery-assisted trans-septal puncture. Catheter Cardiovasc Interv 91:1164-1170
Babaliaros, Vasilis; Greenbaum, Adam B; Kamioka, Norihiko et al. (2018) Bedside Modification of Delivery System for Transcatheter Transseptal Mitral Replacement With POULEZ System and SAPIEN-3 Valve. JACC Cardiovasc Interv 11:1207-1209
Khan, Jaffar M; Rogers, Toby; Schenke, William H et al. (2018) Transcatheter pledget-assisted suture tricuspid annuloplasty (PASTA) to create a double-orifice valve. Catheter Cardiovasc Interv 92:E175-E184

Showing the most recent 10 out of 43 publications