The Core continues to serve the research communities and has made significant impact to science, as evidenced by the list of publications during this period of the report (see below). In the meantime, the first staff of the Core, Dr. Xianayng Fang, has accepted a faculty position offer in Tsinghua University in China and is scheduled to leave the position by the end of year 2014. Dr. Fang has made a great contribution to the community since he took over the responsibility of the Core. Dr. Lixin Fan has joined the Core on July 14. The Core technical transfer has completed after departure of Dr. Fang. In addition, We have installed Rigaku BioSAXS-2000 in Bldg 538/Rm 124. Currently, we are conducting acceptance tests of the instrument and we are expect the instrument go into the service this in the August of 2015. In the meantime, the SAXS Core continues to serve communities with an ever expanding user basis.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Scientific Cores Intramural Research (ZIC)
Project #
1ZICBC011535-04
Application #
9556851
Study Section
Project Start
Project End
Budget Start
Budget End
Support Year
4
Fiscal Year
2017
Total Cost
Indirect Cost
Name
Basic Sciences
Department
Type
DUNS #
City
State
Country
Zip Code
Liu, Yu; Holmstrom, Erik; Zhang, Jinwei et al. (2015) Synthesis and applications of RNAs with position-selective labelling and mosaic composition. Nature 522:368-72
Ithychanda, Sujay Subbayya; Fang, Xianyang; Mohan, Maradumane L et al. (2015) A mechanism of global shape-dependent recognition and phosphorylation of filamin by protein kinase A. J Biol Chem 290:8527-38
Lemak, Alexander; Wu, Bin; Yee, Adelinda et al. (2014) Structural characterization of a flexible two-domain protein in solution using small angle X-ray scattering and NMR data. Structure 22:1862-1874
Chang, Feng-Ming James; Coyne, H Jerome; Cubillas, Ciro et al. (2014) Cu(I)-mediated allosteric switching in a copper-sensing operon repressor (CsoR). J Biol Chem 289:19204-17