The IPDC was one of three components of the molecular imaging aspect of the NIH Roadmap initiative, with the other two being high specificity/high sensitivity probes, and the set-up of an imaging probe database (MICAD). The IPDC produces known and new imaging probes for the NIH research community. The new IPDC laboratories began full operations early in calendar year 2007. The IPDC is now part of the NIH Intramural Program. For a complete listing of our projects, please refer to our website:

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National Heart, Lung, and Blood Institute
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Kuszpit, Kyle; Hollidge, Bradley S; Zeng, Xiankun et al. (2018) [18F]DPA-714 PET Imaging Reveals Global Neuroinflammation in Zika Virus-Infected Mice. Mol Imaging Biol 20:275-283
Basuli, Falguni; Zhang, Xiang; Brugarolas, Pedro et al. (2018) An efficient new method for the synthesis of 3-[18 F]fluoro-4-aminopyridine via Yamada-Curtius rearrangement. J Labelled Comp Radiopharm 61:112-117
Brown, Zachary J; Fu, Qiong; Ma, Chi et al. (2018) Carnitine palmitoyltransferase gene upregulation by linoleic acid induces CD4+ T cell apoptosis promoting HCC development. Cell Death Dis 9:620
Basuli, Falguni; Zhang, Xiang; Jagoda, Elaine M et al. (2018) Rapid synthesis of maleimide functionalized fluorine-18 labeled prosthetic group using ""radio-fluorination on the Sep-Pak"" method. J Labelled Comp Radiopharm 61:599-605
Zhang, Xiang; Dunlow, Ryan; Blackman, Burchelle N et al. (2018) Optimization of 18 F-syntheses using 19 F-reagents at tracer-level concentrations and liquid chromatography/tandem mass spectrometry analysis: Improved synthesis of [18 F]MDL100907. J Labelled Comp Radiopharm 61:427-437
Basuli, Falguni; Zhang, Xiang; Williams, Mark R et al. (2018) One-pot synthesis and biodistribution of fluorine-18 labeled serum albumin for vascular imaging. Nucl Med Biol 62-63:63-70
Brugarolas, Pedro; Sánchez-Rodríguez, Jorge E; Tsai, Hsiu-Ming et al. (2018) Development of a PET radioligand for potassium channels to image CNS demyelination. Sci Rep 8:607
Strickland, Madeleine; Schwieters, Charles D; Göbl, Christoph et al. (2016) Characterizing the magnetic susceptibility tensor of lanthanide-containing polymethylated-DOTA complexes. J Biomol NMR 66:125-139
Basuli, Falguni; Zhang, Xiang; Jagoda, Elaine M et al. (2016) Facile room temperature synthesis of fluorine-18 labeled fluoronicotinic acid-2,3,5,6-tetrafluorophenyl ester without azeotropic drying of fluorine-18. Nucl Med Biol 43:770-772
Sato, Kazuhide; Gorka, Alexander P; Nagaya, Tadanobu et al. (2016) Effect of charge localization on the in vivo optical imaging properties of near-infrared cyanine dye/monoclonal antibody conjugates. Mol Biosyst 12:3046-56

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