Contact PD/PI: SHAKER, REZA NONE Overall: Summary Lead: Reza Shaker MD 5 year direct: NIH/NCATS: $16,140,360 Institution: $34,670,756 Total: $50,811,116 In CTSA 3.0, we will continue our relentless pursuit to transform clinical and translational research in southeastern Wisconsin and the science of clinical and translational (CT) research. We remain focused on and committed to expansion of an engaged, knowledgeable, and high performing CT workforce, refinement of proficient and innovative infrastructure to support CT research and science and removing all impediments to the performance of research. Our long-standing mission to foster a borderless, collaborative, and synergistic research and research training environment for our multi-institutional translational workforce, our community stakeholders and health system members to advance the clinical/translational science research and improve the health of our community, our nation, and beyond continues to drive our direction. We remain committed to working within the CTSA consortium to learn from our colleagues across the nation and to contribute to the growing body of knowledge in the CT field. The tri-lateral mutually learning ecosystem formed by our workforce, the community, and the health system shapes the framework for strategically moving forward and has led to the concept developed in this application of integrated clinical and research ensembles (ICREs) in which patients, clinical investigators, translational researchers, health system representatives, community members, population ambassadors, basic scientists, clinicians and others are brought together. We will further expand our outreach into the communities we serve, reaching deeper into underserved communities, and will incorporate CT research across the life span to pediatric, geriatric and underrepresented populations. In the end, our goal is to use our hard-earned experience and extended capabilities to address the unmet health needs of our patients and our community while persevering to advance our infrastructure and workforce development programs to meet the standards of the developing field of translational science and research.

Public Health Relevance

Our community is in need of better preventive measures, more accurate diagnostics and more effective and efficient therapies. We offer a novel and comprehensive mechanism to address this need through research and education. We propose to create a mutually learning ecosystem that coalesce a myriad of requisite stakeholders including health systems, research enterprises and the community in southeast Wisconsin to work in tandem towards solutions that improve the health outcomes of our citizens.

Agency
National Institute of Health (NIH)
Institute
National Center for Advancing Translational Sciences (NCATS)
Type
Linked Specialized Center Cooperative Agreement (UL1)
Project #
2UL1TR001436-06
Application #
10132100
Study Section
Special Emphasis Panel (ZTR1)
Program Officer
Rosemond, Erica K
Project Start
2015-08-18
Project End
2025-05-31
Budget Start
2020-06-01
Budget End
2021-05-31
Support Year
6
Fiscal Year
2020
Total Cost
Indirect Cost
Name
Medical College of Wisconsin
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
937639060
City
Milwaukee
State
WI
Country
United States
Zip Code
53226
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