The Vanderbilt Institute for Clinical and Translational Research (VICTR) is a highly functional and integrated clinical and translational (C&T) research infrastructure that has raised the quality and scientific rigor of the research conducted at Vanderbilt and longstanding partner Meharry, the nation?s oldest historically black academic health science institution. VICTR will contribute to the mission of the CTSA program while leveraging unique resources and expertise within VICTR?s Hub with these aims: 1) Leverage VICTR?s strong collaborative energy to enhance team science methodologies that propel transdisciplinary research approaches, and integrate proven community engagement principles to stakeholders for all stages of research; 2) Develop, implement and disseminate informatics and data organization methods to promulgate research efficiency, quality, and preparedness and integrate data collection in the conduct of pragmatic trials; 3) Ensure the translational science workforce is diverse and has the skills, knowledge, and resources necessary to advance translation of discoveries; 4) Measurably improve the efficiency, quality, and representativeness of C&T studies by enhancing and systematically integrating services and programs that support highest quality research initiation and conduct; 5) Measurably improve the efficiency and quality of multi-site clinical trials, in collaboration with the TICs and RICs, by leveraging centralized regulatory and legal agreements, providing rapid feasibility and recruitment methods and practices, and creating and disseminating novel clinical trial designs and methodologies; and 6) Utilize unique strengths leveraging novel resources BioVU and PheWAS to guide drug development and repurposing.

Public Health Relevance

The Vanderbilt Institute for Clinical and Translational Research (VICTR) is a highly functional and integrated clinical and translational research infrastructure that has raised the quality and scientific rigor of the research conducted at Vanderbilt and Meharry Medical College. VICTR will contribute to the mission of the CTSA program while leveraging unique resources and expertise within VICTR?s Hub.

Agency
National Institute of Health (NIH)
Institute
National Center for Advancing Translational Sciences (NCATS)
Type
Linked Specialized Center Cooperative Agreement (UL1)
Project #
5UL1TR002243-02
Application #
9490464
Study Section
Special Emphasis Panel (ZTR1)
Program Officer
Gopal-Srivastava, Rashmi
Project Start
2017-06-01
Project End
2022-02-28
Budget Start
2018-03-01
Budget End
2019-02-28
Support Year
2
Fiscal Year
2018
Total Cost
Indirect Cost
Name
Vanderbilt University Medical Center
Department
Type
DUNS #
079917897
City
Nashville
State
TN
Country
United States
Zip Code
37232
Koola, Jejo D; Davis, Sharon E; Al-Nimri, Omar et al. (2018) Development of an automated phenotyping algorithm for hepatorenal syndrome. J Biomed Inform 80:87-95
Empey, Philip E; Stevenson, James M; Tuteja, Sony et al. (2018) Multisite Investigation of Strategies for the Implementation of CYP2C19 Genotype-Guided Antiplatelet Therapy. Clin Pharmacol Ther 104:664-674
Petersen, Kalen J; Reid, Jacqueline A; Chakravorti, Srijata et al. (2018) Structural and functional connectivity of the nondecussating dentato-rubro-thalamic tract. Neuroimage 176:364-371
Zengin-Bolatkale, Hatun; Conture, Edward G; Walden, Tedra A et al. (2018) Sympathetic arousal as a marker of chronicity in childhood stuttering. Dev Neuropsychol 43:135-151
Simpson, Scott A; Field, Suzanne L; Xu, Meng et al. (2018) Effect of Weight Extremes on Ventricular Volumes and Myocardial Strain in Repaired Tetralogy of Fallot as Measured by CMR. Pediatr Cardiol 39:575-584
Hanna, Patrick; Grybek, Virginie; Perez de Nanclares, Guiomar et al. (2018) Genetic and Epigenetic Defects at the GNAS Locus Lead to Distinct Patterns of Skeletal Growth but Similar Early-Onset Obesity. J Bone Miner Res 33:1480-1488
Robinson, Jamie R; Denny, Joshua C; Roden, Dan M et al. (2018) Genome-wide and Phenome-wide Approaches to Understand Variable Drug Actions in Electronic Health Records. Clin Transl Sci 11:112-122
Lewis, Tamorah R; Shelton, Elaine L; Van Driest, Sara L et al. (2018) Genetics of the patent ductus arteriosus (PDA) and pharmacogenetics of PDA treatment. Semin Fetal Neonatal Med 23:232-238
Stone, Amanda L; Bruehl, Stephen; Smith, Craig A et al. (2018) Social learning pathways in the relation between parental chronic pain and daily pain severity and functional impairment in adolescents with functional abdominal pain. Pain 159:298-305
Horn, Leora; Infante, Jeffrey R; Reckamp, Karen L et al. (2018) Ensartinib (X-396) in ALK-Positive Non-Small Cell Lung Cancer: Results from a First-in-Human Phase I/II, Multicenter Study. Clin Cancer Res 24:2771-2779

Showing the most recent 10 out of 162 publications