The proposed Research Training Program in Experimental Medicine and Pathology is designed to prepare veterinarians for independent careers in biomedical research. All trainees (n = 6/yr) will be at the postdoctoral level with appointments as Research Fellows in appropriate departments of Tulane University or LSU. The objective of the program is to provide qualified veterinarians with the requisite research training and experience to enable them to successfully compete for research funding and prepare them for careers in biomedical research. This training grant is a joint venture between Tulane University Health Sciences (includes the School of Medicine, School of Public Health and Tropical Medicine and the TNPRC) and LSU Schools of Medicine and Veterinary Medicine (LSUSVM) with the TNRPC and LSUSVM having the lead roles. Research projects performed while supported by this training grant can be used towards fulfilling the requirements of a PhD at either Tulane or LSU. Training will include instruction in aspects of comparative medicine, pathology and microbial pathogenesis and broad exposure to state-of-the-art investigative tools needed for molecular-mechanism- based biomedical research using animal models. Funding provided by this application will support mentored research training emphasizing bench and translational research using multidisciplinary methods and critical thinking in experimental design, data interpretation, oral and written communication skills and ethical conduct of research. Training methods used will include, but not be limited to, attendance of formal courses offered at Tulane and LSU, participation in research conferences and seminars, supervised work experience, attendance of at least one national and multiple regional meetings, completion of a research project under the supervision of an established investigator and submission of one or more manuscripts describing the work for publication. Trainees also receive instruction in preparation of NIH grant applications and will be expected to submit an NIH grant (K01, KO8 or R21).
(See Instructions): Veterinarians appropriately trained for independent careers in biomedical research are in short supply. Such individuals are needed and play critical roles in high-priority research areas of the NIH categorical institutes. This broad goal of this program is to help fulfill that need and thus to help accelerate biomedical research.
(provided by applicant): None provided.
|Riley, Sean P; Fish, Abigail I; Garza, Daniel A et al. (2016) Nonselective Persistence of a Rickettsia conorii Extrachromosomal Plasmid during Mammalian Infection. Infect Immun 84:790-7|
|Banajee, K H; Verhoeve, V I; Harris, E K et al. (2016) Effect of Amblyomma maculatum (Acari: Ixodidae) Saliva on the Acute Cutaneous Immune Response to Rickettsia parkeri Infection in a Murine Model. J Med Entomol 53:1252-1260|
|Banajee, Kaikhushroo H; Embers, Monica E; Langohr, Ingeborg M et al. (2015) Amblyomma maculatum Feeding Augments Rickettsia parkeri Infection in a Rhesus Macaque Model: A Pilot Study. PLoS One 10:e0135175|
|Kaushal, Deepak; Foreman, Taylor W; Gautam, Uma S et al. (2015) Mucosal vaccination with attenuated Mycobacterium tuberculosis induces strong central memory responses and protects against tuberculosis. Nat Commun 6:8533|
|Phillips, Bonnie L; Mehra, Smriti; Ahsan, Muhammad H et al. (2015) LAG3 expression in active Mycobacterium tuberculosis infections. Am J Pathol 185:820-33|
|Breed, Matthew W; Elser, Samra E; Torben, Workineh et al. (2015) Elite Control, Gut CD4 T Cell Sparing, and Enhanced Mucosal T Cell Responses in Macaca nemestrina Infected by a Simian Immunodeficiency Virus Lacking a gp41 Trafficking Motif. J Virol 89:10156-75|
|Petchampai, Natthida; Sunyakumthorn, Piyanate; Banajee, Kaikhushroo H et al. (2015) Identification of host proteins involved in rickettsial invasion of tick cells. Infect Immun 83:1048-55|
|Schell, John B; Bahl, Kapil; Folta-Stogniew, Ewa et al. (2015) Antigenic requirement for Gag in a vaccine that protects against high-dose mucosal challenge with simian immunodeficiency virus. Virology 476:405-12|
|Sugimoto, Chie; Hasegawa, Atsuhiko; Saito, Yohei et al. (2015) Differentiation Kinetics of Blood Monocytes and Dendritic Cells in Macaques: Insights to Understanding Human Myeloid Cell Development. J Immunol 195:1774-81|
|Mehra, Smriti; Foreman, Taylor W; Didier, Peter J et al. (2015) The DosR Regulon Modulates Adaptive Immunity and Is Essential for Mycobacterium tuberculosis Persistence. Am J Respir Crit Care Med 191:1185-96|
Showing the most recent 10 out of 30 publications