The Vanderbilt Institute for Clinical and Translational Research (VICTR) is a highly functional and integrated clinical and translational (C&T) research infrastructure that has raised the quality and scientific rigor of the research conducted at Vanderbilt and longstanding partner Meharry, the nation?s oldest historically black academic health science institution. VICTR will contribute to the mission of the CTSA program while leveraging unique resources and expertise within VICTR?s Hub with these aims: 1) Leverage VICTR?s strong collaborative energy to enhance team science methodologies that propel transdisciplinary research approaches, and integrate proven community engagement principles to stakeholders for all stages of research; 2) Develop, implement and disseminate informatics and data organization methods to promulgate research efficiency, quality, and preparedness and integrate data collection in the conduct of pragmatic trials; 3) Ensure the translational science workforce is diverse and has the skills, knowledge, and resources necessary to advance translation of discoveries; 4) Measurably improve the efficiency, quality, and representativeness of C&T studies by enhancing and systematically integrating services and programs that support highest quality research initiation and conduct; 5) Measurably improve the efficiency and quality of multi-site clinical trials, in collaboration with the TICs and RICs, by leveraging centralized regulatory and legal agreements, providing rapid feasibility and recruitment methods and practices, and creating and disseminating novel clinical trial designs and methodologies; and 6) Utilize unique strengths leveraging novel resources BioVU and PheWAS to guide drug development and repurposing.

Public Health Relevance

The Vanderbilt Institute for Clinical and Translational Research (VICTR) is a highly functional and integrated clinical and translational research infrastructure that has raised the quality and scientific rigor of the research conducted at Vanderbilt and Meharry Medical College. VICTR will contribute to the mission of the CTSA program while leveraging unique resources and expertise within VICTR?s Hub.

Agency
National Institute of Health (NIH)
Institute
National Center for Advancing Translational Sciences (NCATS)
Type
Linked Specialized Center Cooperative Agreement (UL1)
Project #
1UL1TR002243-01
Application #
9414517
Study Section
Special Emphasis Panel (ZTR1-SRC (99))
Program Officer
Urv, Tiina K
Project Start
2017-06-01
Project End
2022-02-28
Budget Start
2017-06-01
Budget End
2018-02-28
Support Year
1
Fiscal Year
2017
Total Cost
$8,020,564
Indirect Cost
$2,716,958
Name
Vanderbilt University Medical Center
Department
Type
Independent Hospitals
DUNS #
079917897
City
Nashville
State
TN
Country
United States
Zip Code
37232
Moore, Elizabeth E; Hohman, Timothy J; Badami, Faizan S et al. (2018) Neurofilament relates to white matter microstructure in older adults. Neurobiol Aging 70:233-241
Carranza-Leon, Daniel; Octaria, Rany; Ormseth, Michelle J et al. (2018) Association between urinary sodium and potassium excretion and blood pressure and inflammation in patients with rheumatoid arthritis. Clin Rheumatol 37:895-900
Porcari, Giulia S; Beslow, Lauren A; Ichord, Rebecca N et al. (2018) Neurologic Outcome Predictors in Pediatric Intracerebral Hemorrhage: A Prospective Study. Stroke 49:1755-1758
Choi, Leena; Carroll, Robert J; Beck, Cole et al. (2018) Evaluating statistical approaches to leverage large clinical datasets for uncovering therapeutic and adverse medication effects. Bioinformatics 34:2988-2996
Mosley, Jonathan D; Feng, QiPing; Wells, Quinn S et al. (2018) A study paradigm integrating prospective epidemiologic cohorts and electronic health records to identify disease biomarkers. Nat Commun 9:3522
Osborn, Katie E; Liu, Dandan; Samuels, Lauren R et al. (2018) Cerebrospinal fluid ?-amyloid42 and neurofilament light relate to white matter hyperintensities. Neurobiol Aging 68:18-25
Tanner-Smith, Emily E; Finch, Andrew J; Hennessy, Emily A et al. (2018) Who attends recovery high schools after substance use treatment? A descriptive analysis of school aged youth. J Subst Abuse Treat 89:20-27
Chaganti, Shikha; Landman, Bennett A (2018) QUADRATIC: Quality of Dice in Registration Circuits. Proc SPIE Int Soc Opt Eng 10574:
Lutenbacher, Melanie; Elkins, Tonya; Dietrich, Mary S et al. (2018) The Efficacy of Using Peer Mentors to Improve Maternal and Infant Health Outcomes in Hispanic Families: Findings from a Randomized Clinical Trial. Matern Child Health J 22:92-104
Setliff, Ian; McDonnell, Wyatt J; Raju, Nagarajan et al. (2018) Multi-Donor Longitudinal Antibody Repertoire Sequencing Reveals the Existence of Public Antibody Clonotypes in HIV-1 Infection. Cell Host Microbe 23:845-854.e6

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