Patient-centered outcomes research (PCOR) helps people and their caregivers make informed health care decisions, allowing their voices to be heard in assessing the value of healthcare options. PCOR includes comparative effectiveness research (CER), but extends the field and focus to explicit patient involvement throughout research prioritization, conduct and implementation, thus ensuring that the right research questions are asked and the end product is meaningful and useful in practice. It also explicitly recognizes the contribution of a number of types of research, including evidence synthesis, primary data generation, and implementation and dissemination research - all informed directly by the end user of the research. It is, therefore, critical that we train a new generation of young scientists to apply not only the specific methods of PCOR, but to understand the entire system of research as integrated with the patient, physician, family and policy maker perspective. To this end, we must develop a cadre of PCOR investigators who are formally trained in rigorous CER methods and are well versed in best methods for engaging and including stakeholders. This need for a new approach to training is the basis for the rationale and structure of our proposal. The overarching objective of this proposal is to develop a PCOR mentored career development program to train new investigators that demonstrate a commitment to conducting CER as applied to PCOR. The program design reflects four central tenets of clinical investigator training at Vanderbilt-individualized mentored training, protected time, multidisciplinary collaboration, and structured didactic learning complementing practical applications of such learning through conduct of research.
The specific aims of the V-POCKET are: 1. Develop a PCOR-mentored career development program for post-doctoral scientists integrating an individualized mentored research project with experiential or didactic learning. 2. Recruit well-qualified Scholars who are dedicated to a career in PCOR using a strategy that encourages and supports persons from backgrounds underrepresented in biomedical research. 3. Utilize and continually improve an integrated core curriculum that prepares Scholars for a career in CER as applied to PCOR by incorporating formal instruction in the methodological standards proposed by the Methodology Committee of PCORI within a framework of sustained stakeholder involvement. 4. Ensure a multidisciplinary and broad perspective by including scholars and faculty with different educational backgrounds and of different racial and ethnic minority groups. 5. Provide an administrative structure that supports the program, gives it cohesion, guides the selection of mentor teams, and oversees the Scholar's career development. 6. Evaluate the success of the program through both process and outcomes; implement continuous quality improvement procedures to enhance the program.

Public Health Relevance

Patient-centered outcomes research (PCOR) 'helps people and their caregivers make informed health care decisions, allowing their voices to be heard in assessing the value of healthcare options.' It is critical that we train a new generation of young scientists to apply not only the specific methods of PCOR, but to understand the entire system of research as integrated with the patient, physician, family and policy maker perspective to ensure that the information is truly useful to stakeholders and improves public health. This proposal will establish a PCOR mentored career development program at Vanderbilt University to train the next generation of PCOR investigators.

Agency
National Institute of Health (NIH)
Institute
Agency for Healthcare Research and Quality (AHRQ)
Type
Physician Scientist Award (Program) (PSA) (K12)
Project #
6K12HS022990-03
Application #
9117430
Study Section
Special Emphasis Panel (ZHS1)
Program Officer
Hsieh, Chinghui
Project Start
2014-08-01
Project End
2019-07-31
Budget Start
2016-08-01
Budget End
2017-07-31
Support Year
3
Fiscal Year
2016
Total Cost
Indirect Cost
Name
Vanderbilt University Medical Center
Department
Type
DUNS #
079917897
City
Nashville
State
TN
Country
United States
Zip Code
37232
Brunwasser, Steven M; Freres, Derek R; Gillham, Jane E (2018) Youth Cognitive-Behavioral Depression Prevention: Testing Theory in a Randomized Controlled Trial. Cognit Ther Res 42:468-482
McKernan, Lindsey C; Clayton, Ellen W; Walsh, Colin G (2018) Protecting Life While Preserving Liberty: Ethical Recommendations for Suicide Prevention With Artificial Intelligence. Front Psychiatry 9:650
Harper, Kryseana J; Osborn, Chandra Y; Mayberry, Lindsay Satterwhite (2018) Patient-perceived family stigma of Type 2 diabetes and its consequences. Fam Syst Health 36:113-117
Brunwasser, Steven M; Gebretsadik, Tebeb; Gold, Diane R et al. (2018) A new model of wheezing severity in young children using the validated ISAAC wheezing module: A latent variable approach with validation in independent cohorts. PLoS One 13:e0194739
Roumie, Christianne L; Patel, Niral J; Muñoz, Daniel et al. (2018) Design and outcomes of the Patient Centered Outcomes Research Institute coronary heart disease cohort study. Contemp Clin Trials Commun 10:42-49
Bachmann, Justin M; Mayberry, Lindsay S; Wallston, Kenneth A et al. (2018) Relation of Perceived Health Competence to Physical Activity in Patients With Coronary Heart Disease. Am J Cardiol 121:1032-1038
Brunwasser, Steven M; Gillham, Jane E (2018) Identifying Moderators of Response to the Penn Resiliency Program: A Synthesis Study. Prev Sci 19:38-48
Bachmann, Justin M; Shah, Ashish S; Duncan, Meredith S et al. (2018) Cardiac rehabilitation and readmissions after heart transplantation. J Heart Lung Transplant 37:467-476
Beatty, Alexis L; Truong, Michael; Schopfer, David W et al. (2018) Geographic Variation in Cardiac Rehabilitation Participation in Medicare and Veterans Affairs Populations: Opportunity for Improvement. Circulation 137:1899-1908
Rhoten, Bethany Andrews; Murphy, Barbara A; Dietrich, Mary S et al. (2018) Depressive symptoms, social anxiety, and perceived neck function in patients with head and neck cancer. Head Neck 40:1443-1452

Showing the most recent 10 out of 49 publications