Clear

Moreland, Larry W.

Abstract

The contract is for a Consortium for the Longitudinal Evaluation of African Americans with Early Rheumatoid Arthritis registry (CLEAR) which serves to identify genetic and non-genetic prognostic factors of disease outcome using radiographic presence of bony erosions as the primary outcome measure (at 3 years disease duration). The registry (400 completers) will serve as the basis for prospective analyses of factors predictive of the clinical phenotype and outcomes. Four major academic medical centers in the southeast U.S. will gather data which will provide a resource for investigators interested in the genetics of RA in African Americans.

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
• Type: Research and Development Contracts (N01)
• Project #: N01AR002247-000
• Application #: 6358787
• Project Start: 2000-09-28
• Project End: 2005-09-29
• Budget Start: 2000-09-28
• Budget End: 2001-09-29
• Fiscal Year: 2000
• Total Cost: $804,818

Institution

• Name: University of Alabama Birmingham
• Department: Internal Medicine/Medicine
• Type: Schools of Medicine
• DUNS #: 004514360
• City: Birmingham
• State: AL
• Country: United States
• Zip Code: 35294

Publications

Baldassari, Antoine R; Cleveland, Rebecca J; Luong, My-Linh N et al. (2016) Socioeconomic factors and self-reported health outcomes in African Americans with rheumatoid arthritis from the Southeastern United States: the contribution of childhood socioeconomic status. BMC Musculoskelet Disord 17:10

Tamhane, Ashutosh; McGwin Jr, Gerald; Redden, David T et al. (2014) Complementary and alternative medicine use in African Americans with rheumatoid arthritis. Arthritis Care Res (Hoboken) 66:180-9

Baldassari, Antoine R; Cleveland, Rebecca J; Jonas, Beth L et al. (2014) Socioeconomic disparities in the health of african americans with rheumatoid arthritis from the southeastern United States. Arthritis Care Res (Hoboken) 66:1808-17

Tamhane, Ashutosh; Redden, David T; McGwin Jr, Gerald et al. (2013) Comparison of the disease activity score using erythrocyte sedimentation rate and C-reactive protein in African Americans with rheumatoid arthritis. J Rheumatol 40:1812-22

Mikuls, Ted R; Levan, Tricia; Gould, Karen A et al. (2012) Impact of interactions of cigarette smoking with NAT2 polymorphisms on rheumatoid arthritis risk in African Americans. Arthritis Rheum 64:655-64

Bridges Jr, S Louis; Causey, Zenoria L; Burgos, Paula I et al. (2010) Radiographic severity of rheumatoid arthritis in African Americans: results from a multicenter observational study. Arthritis Care Res (Hoboken) 62:624-31

Craig, Steven M; Yu, Fang; Curtis, Jeffrey R et al. (2010) Vitamin D status and its associations with disease activity and severity in African Americans with recent-onset rheumatoid arthritis. J Rheumatol 37:275-81

Reynolds, R J; Kelley, J M; Hughes, L B et al. (2010) Genetic association of htSNPs across the major histocompatibility complex with rheumatoid arthritis in an African-American population. Genes Immun 11:94-7

Zhang, Jie; Redden, David T; McGwin Jr, Gerald et al. (2010) Generalized bone loss as a predictor of three-year radiographic damage in African American patients with recent-onset rheumatoid arthritis. Arthritis Rheum 62:2219-26

Mikuls, Ted R; Sayles, Harlan; Yu, Fang et al. (2010) Associations of cigarette smoking with rheumatoid arthritis in African Americans. Arthritis Rheum 62:3560-8